268224-99-3Relevant academic research and scientific papers
Phosphinic derivatives as new dual enkephalin-degrading enzyme inhibitors: Synthesis, biological properties, and antinociceptive activities
Chen, Huixiong,Noble, Florence,Mothé, Aurélie,Meudal, Hervé,Coric, Pascale,Danascimento, Sophie,Roques, Bernard P.,George, Pascal,Fournié-Zaluski, Marie-Claude
, p. 1398 - 1408 (2007/10/03)
The development of dual inhibitors of the two zinc metallopeptidases, neprilysin (neutral endopeptidase) and aminopeptidase N involved in the inactivation of the opioid peptides, enkephalins, represents an attractive physiological approach in the search f
