26825-18-3

Usage

InChI:InChI=1/C10H16S/c1-9(2)5-6-10(3,4)8-11-7-9/h7-8H2,1-4H3

Upstream product

• 132941-96-9 C₁₀H₁₆SSn(CH(Si(CH₃)3)2)2 
• 2800-87-5 3,3,6,6-tetramethylthiepane-4,5-dione 
• 55168-40-6 5-hydroxy-3,3,6,6-tetramethylthiepan-4-one 
• 26825-19-4 (3,3,6,6-tetramethylthiepane-4,5-diylidene)bis(hydrazine) 
• 13511-38-1 3-chloropivalic acid 
• 21153-31-1 3-(2-carboxy-2-methylpropyl)sulfanyl-2,2-dimethylpropanoic acid 
• 21153-32-2 ethyl 3-(3-ethoxy-2,2-dimethyl-3-oxopropyl)sulfanyl-2,2-dimethylpropanoate 

Downstream Products

• 55849-10-0 2,4,4,8,8-pentamethyl-3-phenyl-2,3,4,5,7,8-hexahydro-thiepino[4,5-d]isoxazole 
• 145083-19-8 1,3-Di-tert-butyl-4,4,8,8-tetramethyl-4,5,7,8-tetrahydro-1H-thiepino[4,5-c]pyrazole 
• 111098-07-8 1,4-Diphenyl-5,6,7,8,9,10-hexahydro-benzocyclooctene 
• 88489-50-3 Δ^1,7-2,2,6,6,8,8-hexamethyl-4-thia-8-silabicyclo<5.1.0>octene 
• 2800-87-5 3,3,6,6-tetramethylthiepane-4,5-dione 
• 55849-06-4 (Z)-3,3,6,6-Tetramethyl-1-thia-4-cyclohepten 
• 139632-70-5 3,3,7,7-Tetramethyl-5-thiatricyclo<7.2.2.0^2.8>trideca-2(8),10-dien 
• 71-43-2 benzene 
• 122982-45-0 (C₆H₂(CH(CH₃)2)3)2SnCCC(CH₃)2CH₂SCH₂C(CH₃)2 
• 1373398-97-0 C₁₇H₂₃N₃S 
• 1395311-87-1 1-benzyl-6-[4-(methoxycarbonyl)benzyl]-4,4,8,8-tetramethyl-4,5,7,8-tetrahydro-1H-thiepino[4,5-d][1,2,3]triazol-6-ium trifluoromethanesulfonate 
• 1395311-84-8 1-[4-(methoxycarbonyl)benzyl]-3,3,6,6-tetramethyl-4,5-didehydro-2,3,6,7-tetrahydrothiepinium trifluoromethanesulfonate 
• 1395311-81-5 CF₃O₃S^(1-)*C₁₈H₂₅OS⁽¹⁺⁾ 

Relevant academic research and scientific papers

TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide-alkyne cycloaddition reactions

We describe the development of TMTH-SulfoxImine (TMTHSI) as a superior click reagent. This reagent combines a great reactivity, with small size and low hydrophobicity and compares outstandingly with existing click reagents. TMTHSI can be conveniently func

Thiacycloalkynes for copper-free click chemistry

The heteroatom helps! The introduction of an endocyclic sulfur atom enables fine-tuning of the reactivity and stability of thiacycloalkynes for copper-free click chemistry. The stabilizing effect of the endocyclic sulfur atom allows the use of highly activated seven-membered rings as reagents for bioorthogonal copper-free click chemistry. Copyright

New tetramethylthiepinium (TMTI) for copper-free click chemistry

A new derivative of the strained 3,3,6,6-tetramethylthiacycloheptyne (TMTH) bearing a functional handle is reported. Following an optimized synthesis, the handle was introduced by mild alkylation of the sulphur atom. The resulting functionalized strained 4,5-didehydro-3,3,6,6-tetramethyl-2,3,6,7- tetrahydrothiepinium (TMTI) proved to be stable and underwent extremely fast [3+2] cycloaddition reaction with benzyl azide in both organic and aqueous solvents. The reaction was equally efficient in cell lysate and serum and therefore opens interesting prospects for chemical-biology applications.