268545-00-2

Upstream product

• 268544-85-0 ethyl 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(methoxycarbonyl)-5-methyl-3-pyrazolecarboxylate 
• 268544-90-7 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(methoxycarbonyl)-5-methyl-3-pyrazolecarboxylic acid 
• 86398-94-9 2,6-dichloro-4-(trifluoromethyl)phenyl hydrazine 
• 127107-00-0 ethyl 2-amino-3-methoxycarbonyl-4-oxo-2-pentanoate 
• 765-30-0 Cyclopropylamine 

Relevant academic research and scientific papers

A new synthetic entry to 3-carboxamido-4-carboxylic acid derivatives of isoxazole and pyrazole

Ethyl 2-amino-3-methoxycarbonyl-4-oxo-2-pentenoate (3) reacts with hydroxylamine or hydrazines to give isoxazole and pyrazole ortho-dicarboxylic acid esters 4 and 5, respectively. Partial hydrolysis of diesters 4 and 5 afforded the corresponding dicarboxy