86398-94-9

Usage

Uses

Used in Chemical Synthesis:
2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE is used as a synthetic intermediate for the production of pyrazolo[4,3-d]isoxazole derivatives, which are important in the development of pharmaceuticals and other chemical compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE is used as a precursor in the synthesis of a range of N-(2,6-dichloro-4-trifluoromethyl)phenyl-N′-(1-phenylethylidene) hydrazines, which have potential applications in the development of new drugs and therapeutic agents. These hydrazines include:
N-(2,6-dichloro-4-trifluoromethyl)phenyl-N′-(1-phenylethylidene)hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-chlorophenyl)ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(3-chlorophenyl)ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-bromophenyl)-ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(3-bromophenyl)ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-methoxyphenyl)ethylidene]-hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-trifluoromethylphenyl)-ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-nitrophenyl)ethylidene]hydrazine
N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(6-methoxy-naphthalen-2-yl)-ethylidene]hydrazine
These hydrazines are synthesized for their potential applications in medicinal chemistry and drug discovery, where they may contribute to the development of new therapeutic agents with novel mechanisms of action.

InChI:InChI=1/C7H6ClF3N2/c8-5-3-4(7(9,10)11)1-2-6(5)13-12/h1-3,13H,12H2

Upstream product

• 24279-39-8 2,6-dichloro-4-(trifluoromethyl)aniline 
• 1336-21-6 ammonium hydroxide 
• 77227-81-7 1,3-dichloro-2-fluoro-5-(trifluoromethyl)benzene 
• 104554-79-2 1,2-dichloro-3-fluoro-5-trifluoromethylbenzene 
• 50594-82-6 1-trifluoromethyl-3,4,5-trichlorobenzene 

Downstream Products

• 268544-85-0 ethyl 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(methoxycarbonyl)-5-methyl-3-pyrazolecarboxylate 
• 24279-39-8 2,6-dichloro-4-(trifluoromethyl)aniline 
• 156819-60-2 2,2-dichloro-1-methylcyclopropyl carboxylic acid N'-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazide 
• 120068-79-3 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole 
• 333994-42-6 2-[2,6-dichloro-4-(trifluoromethyl)phenyl]-3-methyl-4,5,6,7-tetrahydro-2H-indazole 
• 288066-47-7 N'-(2,6-dichloro-4-trifluoromethylphenyl)-chloroacetohydrazide 

Relevant academic research and scientific papers

Phenyl bispyrazole carboxamide derivatives and preparation method and application thereof

The invention provides phenyl bispyrazole carboxamide derivatives and a preparation method and an application thereof; the compounds show relatively good inhibition performance on armyworm under the concentration of 500-100 ppm, a target compound I-6, a c

ENHANCERS OF PROTEIN DEGRADATION

The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof.

Synthesis of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl-1h- pyrazole-4-carbaldehydes

A series of novel 1-[(2,6-dichloro-4-trifluoromethyl)phenyl]-3-aryl- 1Hpyrazole-4-carbaldehydes 6a-i were synthesized using the Vilsmeier-Haack reagent. The structures of all the title compounds have been confirmed by elemental analysis, 1H-NMR

PROCESS FOR PREPARING SUBSTITUTED PHENYLHYDRAZINES

This invention relates to a process for preparing substituted phenylhydrazines of the formula I wherein R has the meaning as indicated in the description, comprising reacting a dichlorofluorobenzene of the formula Il with a hydrazine source selected from

PROCESS FOR PREPARING 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE USING MIXTURES OF DICHLORO-FLUORO-TRIFLUOROMETHYLBENZENES

This invention relates to a process for preparing 2,6-dichloro-4- (trifluoromethyl)phenylhydrazine of the formula (I) wherein a mixture comprising 1,3-dichloro-2-fluoro-5-trifluoromethylbenzene and 1,2-dichloro-3-fluoro-5-trifluoromethylbenzene is reacted with a hydrazine source selected from hydrazine, hydrazine hydrate or acid addition salts of hydrazine, optionally in the presence of at least one organic solvent.

Herbicidal derivatives of 2-(1-aryl-4-cyano-5-pyrazolylmethyleneiminooxy)alkanoic acids

Herbicidal compounds, compositions containing them, and a method for controlling weeds by application of the compositions are disclosed. The herbicidal compounds are 2-(1-aryl-4-cyano-5-pyrazolylmethyleneiminooxy)alkanoic acid derivatives of the structure

Derivatives of N-phenylpyrazoles

N-Phenylpyrazole derivatives of the formula: STR1 wherein R1 represents cyano, nitro, halogen, acetyl or formyl; R2 represents R5 SO2, R5 SO or R5 S in which R5 is optionally halogen substituted alkyl, alkenyl or alkynyl; R3 represents a hydrogen atom or a group NR6 R7 wherein R6 and R7 each represent hydrogen, alkyl, alkenylalkyl, alkynylalkyl, formyl, optionally halogen substituted alkanoyl, optionally halogen substituted alkoxycarbonyl, or alkoxymethyleneamino, halogen, or R6 and R7 together form a cyclic imide and R4 represents a substituted phenyl group possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.

Herbicidal β-pyrazolylacrylic acids

This application discloses herbicidal β-pyrazolylacrylic acids, compositions containing them, methods of preparing them, and methods for controlling undesired plant growth by preemergent or postemergent application of the herbicidal compositions to the lo

Herbicidal compositions based on substituted pyrazolin-5-one derivatives and use thereof

The invention relates to the use of partly known substituted pyrazolin-5-one derivatives of the formula (I) STR1 as herbicides and fungicides, new substituted pyrazolin-5-one derivatives and processes for their preparation.

4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them

Novel herbicidal and plant-growth regulating pyrazoles of the formula STR1 in which R1 represents hydrogen, alkyl or halogenoalkyl, R2 represents nitro or cyano, R3 represents optionally substituted alkyl, optionally subst