26858-31-1

Usage

General Description

2-(2-(4-Chlorophenyl)thiazol-4-yl)ethanaMine, also known as Ciprofloxacin is an antibiotic medication that belongs to the fluoroquinolone class. It is used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, skin infections, and joint and bone infections. Ciprofloxacin works by inhibiting the enzymes DNA gyrase and topoisomerase IV, which are necessary for bacteria to replicate and grow. This ultimately leads to the destruction of the bacterial cell and the resolution of the infection. It is available in various forms, including tablets, oral suspension, and intravenous solution, and is generally well-tolerated, although it can cause some side effects such as nausea, diarrhea, and dizziness.

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 20287-70-1 ethyl 2-(2-(4-chlorophenyl)thiazol-4-yl)acetate 
• 21278-77-3 2-(4-chlorophenyl)thiazole-4-carbaldehyde 
• 18832-93-4 2-(2-(4-chlorophenyl)thiazol-4-yl)acetonitrile 
• 2521-24-6 4-chlorothiobenzamide 

Downstream Products

• 932986-18-0 N-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyramide 
• 40361-70-4 N-{2-[2-(4-chloro-phenyl)-thiazol-4-yl]-ethyl}-acetamide 

Relevant academic research and scientific papers

Substituted pyrimidine compound and application thereof

The present invention discloses a substituted pyrimidine compound, which has a structure represented by a general formula I, wherein each substituent is defined in the specification. According to thepresent invention, the compound has a broad-spectrum bactericidal activity, can provide excellent prevention and control effects on cucumber downy mildew, wheat powdery mildew, corn rust disease, riceblast, cucumber anthracnose and the like, and particularly can provide good prevention effects on powdery mildew, corn rust disease and rice blast.

PROCESS FOR PREPARING A POTENT THIAZOLE COMPOUND, PHARMACEUTICAL FORMULATION AND USES THEREOF

The present invention relates to a process for preparing N-[2-[2-(4-chlorophenyl)-4- thiazolyl] ethyl]-butanamide. The present invention further relates to a pharmaceutical formulation and the use of said pharmaceutical formulation consisting of N-[2-[2-(

Application of compound to preparation of medicine for inhibiting kallikrein KLK7 and synthesis method of compound

The invention belongs to the field of biomedicine and particularly relates to application of a compound to preparation of a medicine for inhibiting kallikrein KLK7 and a synthesis method of the compound. The compound is used for preparing the medicine for inhibiting kallikrein KLK7. The structural formula of the compound is as shown in the description. The compound for inhibiting kallikrein KLK7 can effectively inhibit the activity of KLK7, the synthesis method is easy to implement, and proper auxiliary materials and assistant are added so that the compound can be prepared into medicine preparations for inhibiting the activity of KLK7.

Application and synthetic method of compound in the preparation of a medicine for inhibiting kallikrein KLK7

The invention belongs to the field of biomedicine, and in particular to application and synthetic method of a compound in the preparation of a medicine for inhibiting kallikrein KLK7. The invention provides application of a compound in the preparation of a medicine for inhibiting kallikrein KLK7. The structural formula of the compound is shown as below. The compound for inhibiting kallikrein KLK7 release can effectively inhibit the KLK7 activity. The synthesis method is simple and easy; and suitable excipients and additives can be added to prepare a medicament preparation for inhibiting the activity of KLK7.

Application of compound in preparing medicine for inhibiting kallikrein (KLK7) and synthetic method of compound

The invention belongs to the field of biomedicine, and particularly relates to application of a compound in preparing medicine for inhibiting kallikrein (KLK7) and a synthetic method of the compound. According to the application of the compound in preparing medicine for inhibiting KLK7, the structural formula of the compound is shown in the description. The compound for inhibiting KLK7 can effectively inhibit the activity of KLK7; the synthetic method of the compound is simple and easy to implement, and the compound can be prepared into a pharmaceutical preparation for inhibiting the activity of KLK7 by adding proper accessories and auxiliaries.

Application of compound in preparing medicine for inhibiting kallikrein KLK7 and compounding technology thereof

The invention belongs to the field of biomedicine, and particularly relates to application of a compound in preparing medicine for inhibiting kallikrein KLK7 and a compounding method thereof. In the application of the compound in preparing the medicine for inhibiting the kallikrein KLK7, the structural formula of the compound is as shown in the description. The compound for inhibiting the kallikrein KLK7, provided by the invention, is capable of effectively inhibiting the activity of the KLK7; the compounding method of the compound is simple and easy, and a medicine preparation for inhibiting the activity of the KLK7 can be prepared by adding appropriate auxiliary materials and additives.

COMPOUNDS AND METHODS for the inhibition of HDAC

Disclosed are compounds having the formula: wherein X1, X2, X3, R1, R2, R3, R4, Y, A, Z, L and n are as defined herein, and methods of making and using the same.