26859-66-5

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 35822-58-3 2-bromobenzaldehyde diethyl acetal 

Downstream Products

• 469863-79-4 1-(p-chlorophenyl)-1-methoxymethyl-3-ethoxy-1H-isoindole 
• 74113-21-6 (αRS,1RS)-α,1-Bis(4-chlorophenyl)-3-ethoxy-1H-isoindole-1-ethanol 
• 74113-22-7 (αRS,1SR)-α,1-Bis(4-chlorophenyl)-3-ethoxy-1H-isoindole-1-ethanol 
• 55516-81-9 (αR,3S)-(+)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 
• 55516-84-2 (αS,3S)-(+)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 
• 74164-82-2 (αRS,3RS)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 
• 74164-83-3 (αRS,3SR)-α,3-Bis(4-chlorophenyl)phthalimidine-3-ethanol 
• 55516-87-5 (αR,1R)-(-)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-85-3 (αR,1S)-(-)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 55516-88-6 (αS,1S)-(+)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 74164-80-0 (αRS,1SR)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 74164-78-6 (αRS,1RS)-α,1-Bis(4-chlorophenyl)isoindoline-1-ethanol 
• 54089-77-9 (S)-(+)-3-(4-Chlorophenyl)-3-(4'-chlorophenacyl)phthalimidine 
• 40593-75-7 3-(4-Chlorophenyl)-3-(4'-chlorophenacyl)phthalimidine 

Relevant academic research and scientific papers

A facile synthesis of 1-substituted 3-alkoxy-1h-isoindoles based on the reaction of 2-(dialkoxymethyl)phenyllithiums with nitriles, followed by acid-catalyzed cyclization

A two-step synthesis of 1-substituted 3-alkoxy-1H-isoindoles 4 has been developed. Thus, the reaction of 2-(dialkoxymethyl)phenyllithium compounds, which are easily generated in situ by Br/Li exchange between 1-bromo-2-(dialkoxymethyl)benzenes 1 and BuLi