268737-22-0

Basic information

• Product Name: 4-[3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-benzoic acid methyl ester
• Synonyms: 4-[3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-benzoic acid methyl ester
• CAS NO: 268737-22-0
• Molecular Weight: 379.502
• Mol File: 268737-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-benzoic acid methyl ester(268737-22-0)
• EPA Substance Registry System: 4-[3-(1,1,3,3-tetramethyl-butylamino)-imidazo[1,2-a]pyridin-2-yl]-benzoic acid methyl ester(268737-22-0)

Safety Data

• Hazardous Substances Data: 268737-22-0(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 14542-93-9 1,1,3,3-tetramethylbutane isonitrile 
• 1571-08-0 methyl 4-formylbenzoate 
• 124-41-4 sodium methylate 
• 619-66-9 4-Carboxybenzaldehyde 

Relevant articles and documents

A novel dealkylation affording 3-aminoimidazo[1,2-a]pyridines: Access to new substitution patterns by solid-phase synthesis

The three-component synthesis of 3-aminoimidazo[1,2-a]pyridine derivatives has been extended by a novel acid-induced dealkylation reaction that removes the 1,1,3,3-tetramethylbutyl group derived from the isonitrile input. This reaction was conducted on the solid-phase using the HMBA linker and the resulting products subjected to reductive alkylation using several aldehydes, thereby accessing novel substitution patterns at the 3-position. (C) 2000 Elsevier Science Ltd.