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2'-O-(tert-butyldimethylsilyl)-3'-deoxy-3'-{[(4-nitrophenoxy)carbonyl]methyl}-5'-O-dimethoxytrityl-5-methyluridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

268748-06-7

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268748-06-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 268748-06-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,8,7,4 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 268748-06:
(8*2)+(7*6)+(6*8)+(5*7)+(4*4)+(3*8)+(2*0)+(1*6)=187
187 % 10 = 7
So 268748-06-7 is a valid CAS Registry Number.

268748-06-7Upstream product

268748-06-7Downstream Products

268748-06-7Relevant academic research and scientific papers

Synthesis of amide-linked [(3')CH2CO-NH(5')] nucleoside analogues of small oligonucleotides

Robins, Morris J.,Doboszewski, Bogdan,Nilsson, Bradley L.,Peterson, Matt A.

, p. 69 - 86 (2007/10/03)

We report syntheses of new amide-linked (di-penta)nucleoside analogues of antisense oligonucleotide components. Solution-phase coupling of 3'- (carboxymethyl)-3'-deoxy- and 5'-amino-5'-deoxynucleoside derivatives provides amide dimers. Activated [3'-(carboxymethyl)-3'-deoxy] units with a 5'-azido-5'-deoxy function provide 'masked' 5'-amino-5'-deoxy residues for chain extension, and a 5'-O-DMT-protected unit provides the 5'-terminus for attachment to a phosphodiester linkage.

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