2689-62-5

Basic information

• Product Name: Methyl 2-(triphenylphosphoranyl)propanoate
• Synonyms: 2-METHOXYCARBONYLETHYLTRIPHENYLPHOSPHONIUM BROMIDE;1-Methoxycarbonylethyltriphenylphosphonium Bromide;carbmethoxy Ethyl Triphenyl Phosphonium Bromide;(1-Carboxyethyl)-triphenylphosphonium bromide methyl ester;METHYL 2-(TRIPHENYLPHOSPHORANYL)PROPANOATE;CMETPPB;PHOSPHONIUM,(2-METHOXY-1-METHYL-2-OXOETHYL)TRIPHENYL-,BROMIDE;CarboMethoxy ethyl triphenyl phosphoniuM broMide
• CAS NO: 2689-62-5
• Molecular Formula: Br*C₂₂H₂₂O₂P
• Molecular Weight: 350.39
• EINECS: 1312995-182-4
• Mol File: 2689-62-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 178-180 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: Methyl 2-(triphenylphosphoranyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(triphenylphosphoranyl)propanoate(2689-62-5)
• EPA Substance Registry System: Methyl 2-(triphenylphosphoranyl)propanoate(2689-62-5)

Safety Data

• Hazardous Substances Data: 2689-62-5(Hazardous Substances Data)

Usage

General Description

Methyl 2-(triphenylphosphoranyl)propanoate is a chemical compound with the molecular formula C20H19O2P. It is a white solid at room temperature and is commonly used as a reagent in organic synthesis. Methyl 2-(triphenylphosphoranyl)propanoate contains a phosphoranyl group attached to a propanoate ester, which makes it useful for various chemical reactions and transformations. Methyl 2-(triphenylphosphoranyl)propanoate is often utilized as a ligand in metal-catalyzed reactions and as a precursor in the synthesis of other organic compounds. It is also known for its ability to facilitate asymmetric synthesis and is widely used in the field of organic chemistry.

InChI:InChI=1/C22H22O2P/c1-18(22(23)24-2)25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3/q+1

Upstream product

• 5445-17-0 Methyl 2-bromopropionate 
• 603-35-0 triphenylphosphine 

Downstream Products

• 40277-76-7 methyl (E)-2-methyl-3-(4-nitrophenyl)acrylate 
• 1530-32-1 ethyltriphenylphosphonium bromide 
• 596095-56-6 (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienoic acid methyl ester 
• 1259066-62-0 C₁₉H₂₆O₆ 
• 1259066-60-8 C₁₉H₂₆O₆ 

Relevant articles and documents

Metal-Free Transfer Hydroiodination of C-C Multiple Bonds

The design and a gram-scale synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gaseous hydrogen iodide are described. By initiation with a moderately strong Br?nsted acid, hydrogen iodide is transferred from the surrogate onto C-C multiple bonds such as alkynes and allenes without the involvement of free hydrogen iodide. The surrogate fragments into toluene and ethylene, easy-to-remove volatile waste. This hydroiodination reaction avoids precarious handling of hydrogen iodide or hydroiodic acid. By this, a broad range of previously unknown or difficult-to-prepare vinyl iodides can be accessed in stereocontrolled fashion.

Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment

(Chemical Equation Presented) A synthesis of the C(1)-C(11) fragment of apoptolidin A has been accomplished by a convergent route involving the stereoselective glycosidation of 9 and the Suzuki cross-coupling reaction of bromodienoate 7 and the vinylboran