2689-62-5

Usage

Uses

Used in Organic Synthesis:
Methyl 2-(triphenylphosphoranyl)propanoate is used as a reagent in organic synthesis for its ability to participate in a wide range of chemical reactions and transformations. Its phosphoranyl group provides unique reactivity that can be harnessed in the synthesis of complex organic molecules.
Used as a Ligand in Metal-Catalyzed Reactions:
In the field of catalysis, Methyl 2-(triphenylphosphoranyl)propanoate is utilized as a ligand, enhancing the efficiency and selectivity of metal-catalyzed reactions. Its presence can stabilize metal complexes and influence the course of catalytic processes, leading to improved outcomes in chemical synthesis.
Used as a Precursor in the Synthesis of Other Organic Compounds:
Methyl 2-(triphenylphosphoranyl)propanoate also serves as a precursor in the synthesis of other organic compounds, where its phosphoranyl group can be further modified or used as a building block for the creation of novel molecules with specific properties and applications.
Used in Asymmetric Synthesis:
A notable application of Methyl 2-(triphenylphosphoranyl)propanoate is in asymmetric synthesis, where it aids in the creation of enantiomerically pure compounds. Its ability to induce chirality in reactions is highly valuable in the production of pharmaceuticals and other chiral molecules that require precise stereochemistry.
Used in the Field of Organic Chemistry:
Methyl 2-(triphenylphosphoranyl)propanoate is widely used across the field of organic chemistry, where its unique properties and reactivity contribute to the advancement of synthetic methods and the discovery of new chemical entities. Its applications span across various industries that rely on organic compounds for their products and processes.

InChI:InChI=1/C22H22O2P/c1-18(22(23)24-2)25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3/q+1

Upstream product

• 5445-17-0 Methyl 2-bromopropionate 
• 603-35-0 triphenylphosphine 

Downstream Products

• 596095-56-6 (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienoic acid methyl ester 
• 1259066-62-0 C₁₉H₂₆O₆ 
• 1259066-60-8 C₁₉H₂₆O₆ 
• 40277-76-7 methyl (E)-2-methyl-3-(4-nitrophenyl)acrylate 
• 1530-32-1 ethyltriphenylphosphonium bromide 

Relevant academic research and scientific papers

Metal-Free Transfer Hydroiodination of C-C Multiple Bonds

The design and a gram-scale synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gaseous hydrogen iodide are described. By initiation with a moderately strong Br?nsted acid, hydrogen iodide is transferred from the surrogate onto C-C multiple bonds such as alkynes and allenes without the involvement of free hydrogen iodide. The surrogate fragments into toluene and ethylene, easy-to-remove volatile waste. This hydroiodination reaction avoids precarious handling of hydrogen iodide or hydroiodic acid. By this, a broad range of previously unknown or difficult-to-prepare vinyl iodides can be accessed in stereocontrolled fashion.

A bismuth(III)-catalyzed friedel-crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin

A high yielding route to the (-)-platensimycin core is communicated. This entailed the discovery of Bi(OTf)3 to catalyze a Friedel-Crafts cyclization of a free lactol, supplemented by LiClO4 to suppress the Lewis basicity of the sulfonate group. After TBAF-promoted cyclodearomatization, a diastereoselective conjugate reduction of a dienone was achieved by adopting amine-based organocatalytic rationales to reverse the inherent steric control of the substrate.

Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment

(Chemical Equation Presented) A synthesis of the C(1)-C(11) fragment of apoptolidin A has been accomplished by a convergent route involving the stereoselective glycosidation of 9 and the Suzuki cross-coupling reaction of bromodienoate 7 and the vinylboran

From dicarbonylallene to 1-aryl-3,6-dimethyl-4-aminoaryl-2-pyridones: a one-pot versatile and uncatalyzed synthesis

Reaction of amines with an allenic precursor leads to new 1-aryl-3,6-dimethyl-4-aminoaryl-2-pyridones in good yields. These syntheses can be performed in two distinct steps, allowing the possibility to introduce different substituents in the positions 1 a