269-75-0 Usage
Heterocyclic compound
1H-Pyrazolo[3,4-b]quinoxaline consists of a pyrazole ring fused to a quinoxaline ring.
Crystalline solid
It is a solid with a crystalline structure.
Solubility
It is soluble in organic solvents such as dimethyl sulfoxide and methanol.
Pharmacological properties
It has potential pharmacological properties, including its ability to act as an antagonist at the histamine H1 receptor and its potential as an anti-cancer agent.
Versatile functionalization
The structure of 1H-Pyrazolo[3,4-b]quinoxaline allows for versatile functionalization, making it a valuable starting material for the synthesis of various biologically active compounds.
Unique molecular structure
1H-Pyrazolo[3,4-b]quinoxaline has a unique molecular structure that makes it a molecule of interest for further research and potential drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 269-75-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,6 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 269-75:
(5*2)+(4*6)+(3*9)+(2*7)+(1*5)=80
80 % 10 = 0
So 269-75-0 is a valid CAS Registry Number.
269-75-0Relevant academic research and scientific papers
A new methodology of annelation of five- and seven-membered heterocycles to quinoxalines
Boguslavskiy,Ponizovskiy,Kodess,Charushin
, p. 2175 - 2184 (2007/10/03)
Pyrazolo[3,4-b]-, isoxazolo[4,5-b]-, benzo[2,3]-1,4-diazepino-, and benzo[2,3]-1-4-oxazepinoquinoxalines were prepared by reactions of 2-quinoxalinecarboxaldehyde with 1,2-N,N-, 1,2-N,O and 1,4-N,N- and 1,4-N,O-dinucleophiles.
Quinoxalines X [1]. A new and convenient synthesis of 1H-pyrazolo[3,4-b]quinoxalines (flavazoles)
Sarodnick,Linker
, p. 829 - 836 (2007/10/03)
Quinoxaline-2-aldoximes and -ketoximes (6) react with hydrazine, alkylhydrazines or arylhydrazines under acidic conditions to afford 1H-pyrazolo[3,4-b]quinoxalines (flavazoles) (1). Since the oximes (6) are easily available from phenylenediamine, the herein described methodology provides a convenient two step entry to various functionalized flavazoles. Furthermore, acylation and alkylation of the 1-unsubstituted 1H-pyrazolo[3,4-b]quinoxalines 7 proceeds smoothly and in good yield to afford 31 different flavazoles 11 and 12.
