26903-66-2Relevant academic research and scientific papers
Direct enantioselective organocatalytic hydroxymethylation of aldehydes catalyzed by α,α-diphenylprolinol trimethylsilyl ether
Boeckman Jr., Robert K.,Miller, John R.
scheme or table, p. 4544 - 4547 (2009/12/26)
The direct enantioselective hydroxymethylation of aldehydes utilizing α,α-diphenylprolinol trimethylsilyl ether as an organocatalyst is described. The intermediate α-substituted β-hydroxyaldehydes were not isolated but converted to the more readily isolab
Reactions of 2-substituted epichlorohydrins
Tanyeli,Demir,Akhmedov,Ozgul,Kandemir
, p. 2967 - 2980 (2007/10/03)
2-Substituted epichlorohydrins have been synthesized by starting with 1,2-dichloro acetone and various alkyl and aryl halides via dichlorohydrins followed by cyclization. The reactive 2-substituted epichlorohydrins were subjected to nucleophilic attacking of azide and cyanide ions to afford corresponding β-azido alcohols and α,β-unsaturated nitriles.
