26923-38-6

Basic information

• Product Name: 2-(2,4-Dichloro-phenyl)-acrylonitrile
• Synonyms: 2-(2,4-Dichloro-phenyl)-acrylonitrile
• CAS NO: 26923-38-6
• Molecular Weight: 198.051
• Mol File: 26923-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,4-Dichloro-phenyl)-acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-Dichloro-phenyl)-acrylonitrile(26923-38-6)
• EPA Substance Registry System: 2-(2,4-Dichloro-phenyl)-acrylonitrile(26923-38-6)

Safety Data

• Hazardous Substances Data: 26923-38-6(Hazardous Substances Data)

Upstream product

• 51-80-9 bis-(dimethylamino)methane 
• 6306-60-1 2,4-Dichlorophenylacetonitrile 

Downstream Products

• 108664-50-2 2-(2,4-dichlorophenyl)-4'-chloroacrylanilide 
• 108664-51-3 2-(2,4-Dichloro-phenyl)-1-morpholin-4-yl-propenone 
• 108664-85-3 2-(2,4-Dichloro-phenyl)-acryloyl chloride 
• 108664-84-2 2-(2,4-dichlorophenyl)acrylate 

Relevant articles and documents

Synthesis and Antifungal Activity of a Series of Novel 1,2-Disubstituted Propenones

To find an antifungal agent other than those of the imidazole and triazole series, a new class of 1,2-disubstituted propenones I and II was prepared and tested for antifungal activity.Comparison of the structure-activity relationships showed that the conjugated structure of carbonyl and exomethylene groups in I and II plays an important role in potent antifungal acivity.However, it is noteworthy that compounds 53, 54, and 56, which have a hydroxymethyl or methoxymethyl group instead of an exo-methylene group in I, also showed potent activity.Although many compounds exhibited strong antifungal activity in vitro, none showed activity in vivo of oral efficacy against subacute systemic candidiasis in mice. '