26944-56-9Relevant academic research and scientific papers
Chemoenzymatic synthesis of the trans-dihydrodiol isomers of monosubstituted benzenes via anti-benzene dioxides
Boyd, Derek R.,Sharma, Narain D.,Llamas, Nuria M.,O'Dowd, Colin R.,Allen, Christopher C. R.
, p. 2208 - 2217 (2008/02/09)
Enantiopure cis-2,3-dihydrodiols, available from dioxygenase-catalysed cis-dihydroxylation of monosubstituted benzene substrates, have been used as synthetic precursors of the corresponding trans-3,4-dihydrodiols. The six-step chemoenzymatic route from ci
Enantiopure arene dioxides: Chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols
Boyd,Sharma,O'Dowd,Hempenstall
, p. 2151 - 2152 (2007/10/03)
Enantiopure syn- and anti-arene dioxides are synthesised from cis-dihydrodiol metabolites; anti-benzene dioxides are reduced to enantiopure trans-3,4-dihydrodiols while synbenzene dioxides racemise thermally via 1,4-dioxocins.
Resolution of trans-1,2-Dihydroxy-1,2-dihydrobenzene for the Preparation of Optically Pure Benzene Diol Epoxides. Preparation of Bromo- and Chlorobenzene Diol Epoxides
Ganey, Michael V.,Padykula, Robert E.,Berchtold, Glenn A.,Braun, Andrew G.
, p. 2787 - 2793 (2007/10/02)
The resolution of (+/-)-trans-1,2-dihydroxy-1,2-dihydrobenzene has been accomplished by esterase-catalysed hydrolysis of diacetate (+/-)-5.Peracid epoxidation of (+)-2 and (-)-2 gave diol epoxides (+)-3 and (-)-3, respectively.The synthesis of d
