145107-30-8

Upstream product

• 138913-32-3 (3aS,4R,5R,7aS)-7-chloro-2,2-dimethyl-3a,4,5,7a-tetrahydro-1,3-benzodioxole-4,5-diol 
• 86992-79-2 (1S,2S)-3-Chloro-cyclohexa-3,5-diene-1,2-diol 
• 127666-06-2 (3aS,7aS)-4-chloro-2,2-dimethyl-3a,7a-dihydro-1,3-benzodioxole 

Downstream Products

• 137567-79-4 (1R,2R,3R,4R)-5-cyclohexene-1,2,3,4-tetrol 
• 900791-76-6 (1S,2R,5S,6S)-6-(acetyloxy)-2,5-dibromo-3-chloro-3-cyclohexenyl acetate 
• 26944-56-9 (1R,2R)-4-chloro-3,5-cyclohexadiene-1,2-diol 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of the trans-dihydrodiol isomers of monosubstituted benzenes via anti-benzene dioxides

Enantiopure cis-2,3-dihydrodiols, available from dioxygenase-catalysed cis-dihydroxylation of monosubstituted benzene substrates, have been used as synthetic precursors of the corresponding trans-3,4-dihydrodiols. The six-step chemoenzymatic route from ci

Enantiopure arene dioxides: Chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols

Enantiopure syn- and anti-arene dioxides are synthesised from cis-dihydrodiol metabolites; anti-benzene dioxides are reduced to enantiopure trans-3,4-dihydrodiols while synbenzene dioxides racemise thermally via 1,4-dioxocins.

COMPLEMENTARY ENANTIOSPECIFIC SYNTHESES OF CONDURITOL E EPOXIDES FROM HALOBENZENES

Microbial oxidation of chlorobenzene and bromobenzene gave diols (3), which were converted in stereoselective and chemoselective sequences involving epoxidation/osmylation steps and reduction to the enantiomers of (-)- or (+)-conduritol E epoxide (4).