26946-66-7

Basic information

• Product Name: 1-methoxy-4-(1-methoxy-1-methylethyl)-1-methylcyclohexane
• Synonyms: 1-methoxy-4-(1-methoxy-1-methylethyl)-1-methylcyclohexane;1-Methyl-1-methoxy-4-(1-methoxy-1-methylethyl)cyclohexane
• CAS NO: 26946-66-7
• Molecular Formula: C₁₂H₂₄O₂
• Molecular Weight: 200.31776
• EINECS: 248-127-2
• Mol File: 26946-66-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 219.4°C at 760 mmHg
• Flash Point: 57.8°C
• Appearance: /
• Density: 0.9g/cm³
• Vapor Pressure: 0.177mmHg at 25°C
• Refractive Index: 1.444
• CAS DataBase Reference: 1-methoxy-4-(1-methoxy-1-methylethyl)-1-methylcyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-(1-methoxy-1-methylethyl)-1-methylcyclohexane(26946-66-7)
• EPA Substance Registry System: 1-methoxy-4-(1-methoxy-1-methylethyl)-1-methylcyclohexane(26946-66-7)

Safety Data

• Hazardous Substances Data: 26946-66-7(Hazardous Substances Data)

Usage

Molecular structure

A complex structure consisting of a cyclohexane ring with three substituent groups.

Cyclohexane derivative

Based on a cyclohexane ring with additional substituent groups.

Methoxy group

Attached at position 1.

1-Methoxy-1-methylethyl group

Attached at position 4.

Methyl group

Attached at position 1.

Industrial applications

Commonly used in pharmaceutical and chemical industries.

Solvent properties

Acts as a solvent in various processes.

Organic synthesis

Potential use in the synthesis of more complex organic molecules.

Building block

Serves as a starting point for creating more complex molecular structures.

Biological and pharmacological activities

Possesses potential activities that warrant further study and development.

InChI:InChI=1/C12H24O2/c1-11(2,13-4)10-6-8-12(3,14-5)9-7-10/h10H,6-9H2,1-5H3

Upstream product

• 5989-27-5 D-limonene 
• 80-56-8 rac-α-pinene 
• 67-56-1 methanol 
• 138-86-3 limonene. 
• 98-55-5 terpineol 

Relevant articles and documents

Selective methoxylation of limonene over ion-exchanged and acid-activated clays

In this study, we report the use of clay-based catalysts in the methoxylation of limonene, for the selective synthesis of α-terpinyl methyl ether. Na-SAz-1, Ca-SWy-2 and Sap-Ca source clays and a montmorillonite (SD) from Porto Santo, Madeira Archipelago, Portugal were modified by (i) ion-exchange with Al, Fe, Ni and Na and (ii) acid activation, to produce catalysts with markedly different acidic and textural properties. The lack of activity of Ni2+-SAz-1 (with Lewis acidity maximized), provided evidence that the process occurs preferentially on Bro?nsted acid sites. The catalysts based on the high layer-charge SAz-1 montmorillonite proved to be the most active. Ion-exchange with Al3+, followed by thermal activation at 150°C, afforded the highest number of Br?nsted acid sites located in the clay gallery and this coincided with the maximum catalytic activity. The influence of various reaction conditions, to maximize limonene conversion and selectivity, was studied over Al-SAz-1. When the reaction was performed for 20 h at 40°C, the conversion reached 71% with 91% selectivity to the mono-ether. Mild acid activation (1 M HCl, 30 min, reflux) of the raw SAz-1 clay leads to a material with a good catalytic behaviour (slightly inferior to Al-SAz-1), while any increase in the severity of the acid-treatment (6 M HCl, 30 min, reflux), caused a marked decrease in catalytic activity.