2695-67-2Relevant academic research and scientific papers
An investigation of the scope of the 1,7-electrocyclization of α,β:γ,δ-conjugated azomethine ylides
Zhang, Weimin,Ning, Fuqiang,Váradi, Linda,Hibbs, David E.,Platts, James A.,Nyerges, Miklós,Anderson, Rosaleen J.,Groundwater, Paul W.
, p. 3621 - 3629 (2014/05/20)
Substituents on the diene component have little influence on the periselectivity of the cyclizations of α,β:γ,δ-conjugated azomethine ylides, with 1,7-electrocyclizations predominating. In some cases, subtle changes to these substituents can, however, influence the product formed, through their effect on the relative energies of the transition states for the 1,5- (6π) and 1,7-electrocyclization (8π) processes. The most striking changes in periselectivity occur for phenylethenyl-substituted azomethine ylides 3d-f, which can give either a pyrroline 4d,f or dihydrobenzazepine 6e, depending upon the alkene configuration.
NHC-catalyzed oxidative cyclization reaction for the synthesis of 3-substituted phthalides
Youn, So Won,Song, Hyoung Sub,Park, Jong Hyub
supporting information, p. 2388 - 2393 (2014/04/03)
An efficient NHC-catalyzed domino oxidation/oxa-Michael addition reaction of 2-alkenylbenzaldehydes has been developed to afford 3-substituted phthalides bearing a C3-stereogenic center with a broad substrate scope and wide functional group tolerance. The preliminary results of the asymmetric process have been provided as well. the Partner Organisations 2014.
Synthesis of substituted 2-arylindanes from e -(2-stilbenyl)methanols via lewis acid-mediated cyclization and nucleophililc transfer from trialkylsilyl reagents
Sarnpitak, Pakornwit,Trongchit, Kanokrat,Kostenko, Yulia,Sathalalai, Supaporn,Gleeson, M. Paul,Ruchirawat, Somsak,Ploypradith, Poonsakdi
, p. 8281 - 8296 (2013/09/24)
A preparative method for the synthesis of functionalized 2-arylindanes has been developed via the Lewis acid-mediated ring closure of stilbenyl methanols followed by nucleophilic transfer from trialkylsilyl reagents. The reactions gave the corresponding p
AuI-catalyzed intramolecular cyclization of 2-alkenylphenyl carbonyl compounds: Exploring the oxophilic Lewis acidity of AuI species
Jagdale, Arun R.,Youn, So Won
supporting information; experimental part, p. 3904 - 3910 (2011/09/15)
A AuI-catalyzed intramolecular cyclization reaction of 2-alkenylphenyl carbonyl compounds to afford a variety of indene, indenol, and indanone ring systems was developed. In this process, AuI serves to activate the carbonyl group of β-keto esters, aldehydes, and ketones, preferentially exhibiting oxophilicity in the presence of C-C multiple bonds. Furthermore, β-keto esters could participate as the electrophilic partner in reactions with carbon nucleophile such as alkenes. Copyright
