79205-42-8Relevant academic research and scientific papers
NHC-catalyzed oxidative cyclization reaction for the synthesis of 3-substituted phthalides
Youn, So Won,Song, Hyoung Sub,Park, Jong Hyub
, p. 2388 - 2393 (2014/04/03)
An efficient NHC-catalyzed domino oxidation/oxa-Michael addition reaction of 2-alkenylbenzaldehydes has been developed to afford 3-substituted phthalides bearing a C3-stereogenic center with a broad substrate scope and wide functional group tolerance. The preliminary results of the asymmetric process have been provided as well. the Partner Organisations 2014.
Stereoselective synthesis of hydroxy stilbenoids and styrenes by atom-efficient olefination with thiophthalides
Mitra, Prithiba,Shome, Brateen,Ranjan De, Saroj,Sarkar, Anindya,Mal, Dipakranjan
, p. 2742 - 2752 (2012/11/07)
The synthesis of stilbenoids and styryl carboxylic acids is accomplished with high E-stereoselectivity by olefination of aldehydes with thiophthalides under basic conditions. The olefination is highly atom-efficient as it only loses elemental sulfur during the reaction. This olefination, in conjunction with retro Kolbe-Schmitt reaction, allows facile synthesis of E-hydroxystilbenoids with minimal employment of protecting groups. This study also discloses two important findings: formation of i) 4-methylsulfanyl isocoumarins and ii) an 2-arylindenone. The Royal Society of Chemistry 2012.
The Synthesis and Anti-geotropic Activity of o-Arylethenylbenzoic Acids
Teitei, Tsutomu
, p. 1669 - 1674 (2007/10/02)
Fourteen new and three known o-arylethenylbenzoic acids (10-18), required for testing as potential plant growth regulators, have been synthesized by the Wittig reaction.The cis- and trans-isomers were separated by fractional crystallization and identified by NMR spectroscopy.The preliminary assay results on cress seedlings are reported and show that both geometric isomers appear to have nearly identical anti-geotropic activity in this test system.
