26952-97-6Relevant academic research and scientific papers
Intra- and Intermolecular α-Sulfamidoalkylation Reactions
Lee, Chai-Ho,Kohn, Harold
, p. 6098 - 6104 (2007/10/02)
The utility of α-sulfamidoalkylation processes for the generation of sulfamides has been examined.Select aryl-substituted sulfamides were prepared and then treated with acid.Both intra- and intermolecular α-sulfamidoalkylation transformations were observed to proceed in moderate to good yields.The pathways for these reactions are discussed.The generality of these processes has been demonstrated using N,N'-di(aryl-substituted)sulfamides, and the utility of these reactions was examined for the preparation of cyclic sulfamides of novel structure.
