26973-80-8

Basic information

• Product Name: 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID
• Synonyms: 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID;7-(a-Bromoacetamido)cephalosporanicacid;3[(Acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-(6R-trans)-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylicacid;7-(-Bromoacetamido)cephalosporanic acid;(6R-trans)-3-[(Acetyloxy)Methyl]-7-[(broMoacetyl)aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;7-(2-BroMoacetaMido)cephalosporanic Acid;7-BroMoacetylaMinocephalosporanic Acid;Cefathiamidine Impurity 1
• CAS NO: 26973-80-8
• Molecular Formula: C₁₂H₁₃BrN₂O₆S
• Molecular Weight: 393.21042
• Product Categories: Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;MTS & Sulfhydryl Active Reagents;Pharmaceuticals
• Mol File: 26973-80-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 711.2±60.0 °C(Predicted)
• Appearance: /
• Density: 1.81±0.1 g/cm3(Predicted)
• Storage Temp.: Amber Vial, Refrigerator, Under inert atmosphere
• Solubility: Chloroform, Dichloromethane, Dimethyl Sulfoxide
• PKA: 2.67±0.50(Predicted)
• CAS DataBase Reference: 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID(26973-80-8)
• EPA Substance Registry System: 7-(ALPHA-BROMOACETAMIDO)CEPHALOSPORANIC ACID(26973-80-8)

Safety Data

• Hazardous Substances Data: 26973-80-8(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Solid

Uses

An analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA). Can inhibit and specifically alkylate GL-7-ACA acylase (C130) from Pseudomonas sp.130 by forming a carbon-carbon bond between BA-7-ACA and the C-2 on indole ring of Trp-β4 residue of C130.

Upstream product

• 598-21-0 2-Bromoacetyl bromide 
• 957-68-6 7-Aminocephalosporanic acid 

Downstream Products

• 33075-00-2 (6R,7R)-3-(acetyloxymethyl)-7-[[2-[N,N'-di(propan-2-yl)carbamimidoyl]sulfanylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 67365-88-2 7-(2'-aminoethylthio)-acetamido-cephalosporanic acid 
• 60458-29-9 7-[2-(4,5-dihydro-5-imino-1,3,4-thiadiazol-2-ylthio)acetamido]cephalosporanic acid 
• 34409-23-9 4-[((6R)-3-acetoxymethyl-2-carboxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7t-ylcarbamoyl)-methylsulfanyl]-1-methyl-pyridinium betaine 
• 74179-47-8 (6R)-3-acetoxymethyl-7t-[2-(2-naphthalen-2-yl-2-oxo-ethylsulfanyl)-acetylamino]-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 74179-46-7 (6R)-3-acetoxymethyl-7t-[2-(3-hydroxy-naphthalene-2-carbonylsulfanyl)-acetylamino]-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 33074-98-5 (6R)-3-acetoxymethyl-7t-[2-(N,N'-diethyl-carbamimidoylsulfanyl)-acetylamino]-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 27910-38-9 (6R)-3-acetoxymethyl-7t-(2-naphthalen-2-ylsulfanyl-acetylamino)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 21593-23-7 cephapirin 
• 21593-22-6 (6R)-3-acetoxymethyl-8-oxo-7t-(2-pyridin-2-ylsulfanyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 21593-24-8 (6R)-3-acetoxymethyl-8-oxo-7t-(2-pyridin-3-ylsulfanyl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid