26977-06-0

Upstream product

• 26977-09-3 N-(1-methylethyl)-4-oxo-4-phenyl-butyramide 
• 33553-82-1 4-chloro-1-phenyl-1-butanol 
• 75-31-0 isopropylamine 
• 939-52-6 4-chloro-1-phenylbutan-1-one 
• 1955-39-1 5-phenyl-3H-furan-2-one 
• 100-52-7 benzaldehyde 
• 223113-77-7 N-Isopropyl-3-phenylsulfanylpropylamine 

Downstream Products

• 179742-05-3 N-isopropyl-4-phenylbutan-1-amine 
• 179742-04-2 RS-1-isopropyl-2-phenylpyrrolidine 

Relevant academic research and scientific papers

Nitrogen-containing remote functionalised organolithium compounds by reductive opening of five- and six-membered heterocycles

The reaction of different five- or six-membered nitrogen- containing heterocycles such as N-isopropyl-2-phenylpyrrolidine (1), N-phenyl-3-pyrroline (6), N-phenylisoindoline (10), N- phenyltetrahydroisoquinoline (13) and N- methyltetrahydroisoquinoline (19

Elevation of HDL cholesterol by N-[4-[(aminothioxomethyl) hydrazono]-4-arylbutyl]amides

This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of the formula wherein: R1, R2, and R3 are independently hydrogen, C1-C6 alkyl or -(CH2)0-6Ph where Ph is phenyl is optiona

Functionalized organolithium compounds of DTBB-catalyzed sulfur-lithium exchange

The successive reaction of β- or γ-hydroxy or amino phenyl thioethers (1,4) with butyllithium and an excess of lithium powder in the presence of a catalytic amount of DTBB in THF at - 78°C leads to the formation of the corresponding β- or γ-functionalized organolithium compounds 2 or 5, respectively, which by treatment with different electrophiles [D2O, t- BuCHO, PhCHO, Me2CO, (CH2)4CO, (CH2)5CO] at temperatures ranging between - 78°C and room temperature yields, after hydrolysis with water, the expected functionalized alcohols or amines 3 or 6, respectively, in a completely regioselective manner.