26977-11-7Relevant academic research and scientific papers
Stereoselective synthesis of 3,4-di-substituted mercaptolactones via photoredox-catalyzed radical addition of thiophenols
Kouser, Farzana,Sharma, Vijay Kumar,Rizvi, Masood,Sultan, Shaista,Chalotra, Neha,Gupta, Vivek K.,Nandi, Utpal,Shah, Bhahwal Ali
, p. 2161 - 2166 (2018/05/05)
A visible light mediated radical addition of thiophenols on 4-phenylbut-3-enoic acids to give diastereoselective synthesis of 3,4-disubstituted γ-lactones is reported. The reaction precludes the conventional prerequisite of conjugate addition. Furthermore, the lactones were successfully utilized in the synthesis of γ-ketoamides.
Palladium-catalyzed selective hydrogenolysis of N-alkyl(aryl)-substituted γ-keto amides as an approach to γ-lactams or linear amides
Turova,Berezhnaya,Starodubtseva,Vinogradov
, p. 1065 - 1068 (2016/02/09)
A palladium-catalyzed hydrogenolysis of N-substituted γ-keto amides can proceed with participation of tautomeric 5-hydroxypyrrolidin-2-ones and give either pyrrolidin-2-ones, or linear amides, or their mixtures, depending on the substrate structure.
