27006-02-6

Basic information

• Product Name: 4-BroMo-3,5-diMethylbenzyl alcohol
• Synonyms: 4-BroMo-3,5-diMethylbenzyl alcohol;(4-BroMo-3,5-diMethylphenyl)Methanol;4-Bromo-3,5-dimethylbenzenemethanol
• CAS NO: 27006-02-6
• Molecular Formula: C₉H₁₁BrO
• Molecular Weight: 215.08704
• EINECS: -0
• Mol File: 27006-02-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-BroMo-3,5-diMethylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMo-3,5-diMethylbenzyl alcohol(27006-02-6)
• EPA Substance Registry System: 4-BroMo-3,5-diMethylbenzyl alcohol(27006-02-6)

Safety Data

• Hazardous Substances Data: 27006-02-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-3,5-dimethylbenzyl alcohol, also known as 3,5-dimethyl-4-bromobenzyl alcohol, is a compound with the chemical formula C9H11BrO. It is a white to light yellow solid with a strong odor and is commonly used in the pharmaceutical and chemical industries as an intermediate or starting material for the synthesis of various organic compounds. This chemical is also used as a reagent in the production of different types of drugs, particularly those related to benzodiazepines, which are a class of psychoactive drugs with sedative, hypnotic, and anxiolytic properties. Additionally, 4-Bromo-3,5-dimethylbenzyl alcohol is an important building block in the synthesis of flavors and fragrances, making it a versatile and valuable compound in the field of organic chemistry.

Upstream product

• 7697-32-7 4-bromo-3,5-dimethylbenzoic acid 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 74973-54-9 (4-bromo-3,5-dimethylphenyl)methylene diacetate 
• 100189-84-2 2,5-dibromo-1,3-dimethylbenzene 
• 400822-47-1 4-bromo-3,5-dimethylbenzaldehyde 

Downstream Products

• 26965-70-8 4-Chlormethyl-2,6-dimethyl-brombenzol 
• 74973-55-0 2-bromo-5-(methoxymethyl)-1,3-dimethylbenzene 
• 7697-32-7 4-bromo-3,5-dimethylbenzoic acid 
• 910470-66-5 2-bromo-5-tert-butoxymethyl-1,3-dimethyl-benzene 
• 74973-56-1 2-(4-methoxymethyl-2,6-dimethylphenyl)ethanol 
• 79801-57-3 2-(3-bromo-4-methoxymethyl-2,6-dimethylphenyl)ethanol 
• 79801-58-4 methyl 3-(2-hydroxyethyl)-6-methoxymethyl-2,4-dimethylbenzoate 
• 74973-60-7 methyl 3-(2-acetoxyethyl)-6-methoxymethyl-2,4-dimethylbenzoate 
• 74973-57-2 1-bromo-3(2-(tetrahydro-2H-pyran-2-yl)oxyethyl)-6-methoxymethyl-2,4-dimethylbenzene 
• 74973-59-4 methyl 3-(2-(tetrahydro-2H-pyran-2-yl)oxyethyl)-6-methyoxymethyl-2,4-dimethylbenzoate 
• 35510-00-0 2-bromo-5-(bromomethyl)-1,3-dimethylbenzene 
• 1458654-31-3 4-(4-bromo-3,5-dimethylphenyl)butan-2-one 

Relevant articles and documents

Oxidation of Iodo- and Bromo-Substituted Polymethylbenzenes in the System PbO2–CF3COOH–CH2Cl2

The oxidation of mono- and diiodo- and -bromo-substituted polymethylbenzenes (mesitylene and durene) in the system PbO2–CF3COOH–CH2Cl2 at room temperature (2–70 h) leads mainly to the formation of iodo- and brom

ANTIDIABETIC TRICYCLIC COMPOUNDS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Total synthesis of pterosines B and C via a photochemical key step

A total synthesis of pterosines B and C is reported. Starting with a fourfold substituted benzene derivative, the introduction of the remaining substituents is mainly based on Sonogashira couplings followed by different transformations of the ethyne moiety. The key step is a photochemical ring-closure of an α-mesyloxy ketone forming the 1-indanone skeleton. Georg Thieme Verlag Stuttgart.