270088-59-0

Basic information

• Product Name: 1,6-anhydro-2-deoxy-2-iodo-4-O-(p-toluenesulfonyl)-β-D-glucopyranose
• Synonyms: 1,6-anhydro-2-deoxy-2-iodo-4-O-(p-toluenesulfonyl)-β-D-glucopyranose
• CAS NO: 270088-59-0
• Molecular Weight: 426.229
• Mol File: 270088-59-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,6-anhydro-2-deoxy-2-iodo-4-O-(p-toluenesulfonyl)-β-D-glucopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-anhydro-2-deoxy-2-iodo-4-O-(p-toluenesulfonyl)-β-D-glucopyranose(270088-59-0)
• EPA Substance Registry System: 1,6-anhydro-2-deoxy-2-iodo-4-O-(p-toluenesulfonyl)-β-D-glucopyranose(270088-59-0)

Safety Data

• Hazardous Substances Data: 270088-59-0(Hazardous Substances Data)

Upstream product

• 139437-39-1 1,6-anhydro-2-deoxy-2-iodo-β-D-glucopyranose 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 270088-66-9 4-amino-1,6-anhydro-2,4-dideoxy-β-D-arabino-hexopyranose 
• 270088-60-3 1,6-anhydro-2-deoxy-4-O-(p-toluenesulfonyl)-β-D-glucopyranose 

Relevant articles and documents

Synthesis and antitumour activity of a new series of nitrosoureido sugars

New nitrosoureido derivatives of di- or tri-deoxy-sugars have been synthesized. Very potent antitumour activity against L1210 leukaemia was exhibited by the compounds derived from methyl 3-amino-3,4-dideoxy-β- and α- and 4-amino-2,4-dideoxy-β- and α-D-arabino-hexopyranosides, 24, 26, 28 and 29, respectively. In further evaluation against B16 melanocarcinoma bearing mice, only compounds 24 and 26 displayed significant activity. Owing to its lower acute toxicity, methyl 3-[3-(2-chloroethyl)-3-nitrosoureido]- 3,4-dideoxy-β-D-arabino-hexopyranoside 24 appeared as the best candidate for preclinical studies. (C) 2000 Editions scientifiques et medicales Elsevier SAS.