27049-62-3Relevant academic research and scientific papers
Three component reaction of aryl diazonium salt with sulfonamide & actonitrile to synthesize N-sulfonyl amidine
Zhang, Yuan,Chen, Zili
supporting information, p. 4183 - 4186 (2018/10/24)
A new method was developed to prepare N-sulfonyl amidine compounds through three-component reaction of aryl diazonium salts with sulfonamides and acetonitrile, in which, nitrilium ion intermediate, generated from the reaction of aryldiazonium salt with nitrile, was subsequently trapped by sulfonamides. A series of N-sulfonyl amidine derivatives were synthesized by using various types of aryl diazonium salts, sulfonamides and nitriles. In addition, indolyl imine products could also be prepared by using indole as the nucleophile to trap nitrilium ion intermediate.
Interception of Secondary Amide Ylide with Sulfonamides: Catalyst-Controlled Synthesis of N-Sulfonylamidine Derivatives
Chen, Jijun,Long, Wenhao,Yang, Yonggang,Wan, Xiaobing
supporting information, p. 2663 - 2666 (2018/05/22)
A novel, secondary amide activation strategy has been developed through the in situ generation of ylides from amides and diazoacetates. Under the developed reaction conditions, Mn-catalyzed ylide formation and interception reaction by sulfonamide delivered a variety of N-sulfonylamidines. Notably, when highly active Zn(OTf)2 was used as the catalyst, further N-H insertion products were obtained. In contrast with traditional methods, our amide activation strategy is distinguished by accessible starting material, inexpensive catalyst, and broad substrate scope.
Evaluation of dipole moment and electrophilicity on the nature of click-type coupling reaction between thioamide and sulfonyl azide
Aswad, Muhammad,Chiba, Junya,Tomohiro, Takenori,Hatanaka, Yasumaru
, p. 1313 - 1316 (2018/03/26)
A cooperated experimental and computational investigation on sulfonyl amidine formation from thioamides and sulfonyl azides is described. The data support a non-concerted two-step pathway for the coupling reaction and also indicate that dipole moment of t
SYNTHESIS OF TOSYLAMIDINES FROM THIOAMIDES.
Zelenskaya,Kozinskii,Nazarenko,Ranskii
, p. 1071 - 1072 (2007/10/02)
The authors found in the course of development of methods for synthesis of 5-amino-1,2,3-thiadiazoles that the reaction of tosyl azide with thioacetamide (Ia) and with thioacetanilide (Ib) proceeds at the C equals S bond with formation of N-tosylacetamidi
