27087-06-5

Usage

InChI:InChI=1/C7H3ClN2O4/c8-3-1-4-6(14-7(11)9-4)2-5(3)10(12)13/h1-2H,(H,9,11)

Upstream product

• 95-25-0 5-chloro-2-benzoxazolinone 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 6358-07-2 2-amino-4-chloro-5-nitrophenol 

Downstream Products

• 27087-09-8 6-benzenesulfonylimino-5-chloro-6H-benzooxazol-2-one 
• 493033-59-3 3-N-benzyl-5-chloro-6-nitro-benzoxazol-2-one 
• 64037-30-5 6-amino-5-chlorobenzo[d]oxazol-2(3H)-one 
• 27087-07-6 6-benzenesulfonylamino-5-chloro-3H-benzooxazol-2-one 

Relevant academic research and scientific papers

Design, Synthesis and Herbicidal Activities of Tetrahydroisoindoline-1,3-dione Derivatives Containing Alkoxycarbonyl Substituted 2-Benzoxazolinone

Several different alkoxycarbonyl-substituted 2-benzoxazolinone moieties have been incorporated into a tetrahydroisoindoline-1,3-dione scaffold to provide 25 compounds (1a-1u and 2a-2d). The structures of these compounds were confirmed by 1H and 13C NMR, HRMS and X-ray single-crystal diffraction. Some of these compounds (1g, 1h, 1j, 1k) exhibited excellent herbicidal activities against Abutilon theophrasti, Amaranthus retroflexus and Echinochloa crus-galli at a rate of 375 g AI·ha-1. Among them, compounds 1h and 1j displayed the best post-emergence herbicidal effect against Abutilon theophrasti with ED50 values of 1.8 and 5.3 g AI·ha-1, respectively, which are superior to that of the commercial acifluorfen (44.3 g AI·ha-1). Field trials demonstrated that compound 1h exhibited similar herbicidal activity to a high concentration atrazine, and found to be safer for maize than atrazine. The results of this study therefore show that compound 1h could potentially be used as a post-emergence herbicide for maize fields. Two series of tetrahydroisoindoline-1,3-diones containing an alkoxycarbonyl substituted 2-benzoxazolinone moiety were designed and synthesized. Compound 1h displayed excellent herbicidal effect against Abutilon theophrasti with ED50 values of 1.8 g AI·ha-1, and compound 1h could potentially be used as a new post-emergence herbicide for maize fields.

AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS

Compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for t

6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them

Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: wherein Y is halogen or a substituent group linked to the rest of the compound by a hetero atom, and R′ is a group containing at least 8 carbon atoms. Also

6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them

Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: wherein ???Y is halogen or a substituent group linked to the rest of the compound by a hetero atom, and ???R' is a group containing at least 8 carbon atoms

Benzothiazol-2-one-3-alkanoic acids and esters and aldose reductase inhibiting compositions thereof

A pharmaceutical composition comprising certain benzothiazoline alkanoic acid derivatives for the prevention and treatment of various diabetic complications, said derivatives being inhibitors of aldose reductase.