27087-14-5Relevant articles and documents
Synthesis of multifunctional 4-hydroxymethyl 2-oxazolidinones from glycidyl carbamate derivatives catalyzed by bicyclic guanidine
Yoshida, Yoshiaki,Endo, Takeshi
, (2021)
4-Hydroxymethyl 2-oxazolidinones have been successfully synthesized under mild conditions by the intramolecular cyclization of glycidyl carbamate derivatives with a bicyclic guanidine as the efficient catalyst. This reaction system, which is also applicab
Irreversible inactivation of papain and cathepsin B by epoxidic substrate analogues
Giordano, C.,Gallina, C.,Consalvi, V.,Scandurra, R.
, p. 479 - 487 (2007/10/02)
Epoxidic substrate analogues related to allylamine (4a-4e) and allyl alcohol (5a-5f) were synthesized and tested as models of cysteine-protease inhibitors.They proved to be irreversible inhibitors of papain and cathepsin B with pseudo-first-order inactiva