27087-14-5Relevant articles and documents
Synthesis of multifunctional 4-hydroxymethyl 2-oxazolidinones from glycidyl carbamate derivatives catalyzed by bicyclic guanidine
Yoshida, Yoshiaki,Endo, Takeshi
, (2021)
4-Hydroxymethyl 2-oxazolidinones have been successfully synthesized under mild conditions by the intramolecular cyclization of glycidyl carbamate derivatives with a bicyclic guanidine as the efficient catalyst. This reaction system, which is also applicab
4-Hydroxymethyl-substituted oxazolidinone synthesis by tetraarylphosphonium salt-catalyzed reactions of glycidols with isocyanates
Toda, Yasunori,Tanaka, Shoya,Gomyou, Shuto,Kikuchi, Ayaka,Suga, Hiroyuki
supporting information, p. 5761 - 5764 (2019/05/24)
Preparation of 4-hydroxymethyl-substituted oxazolidinones including optically active ones, in which tetraarylphosphonium salts catalyze the reaction of glycidol with isocyanates effectively, is described. The neutral catalysis facilitates glycidol additio
Irreversible inactivation of papain and cathepsin B by epoxidic substrate analogues
Giordano, C.,Gallina, C.,Consalvi, V.,Scandurra, R.
, p. 479 - 487 (2007/10/02)
Epoxidic substrate analogues related to allylamine (4a-4e) and allyl alcohol (5a-5f) were synthesized and tested as models of cysteine-protease inhibitors.They proved to be irreversible inhibitors of papain and cathepsin B with pseudo-first-order inactiva