2711-58-2Relevant articles and documents
The crystalline forms of nine hydrochloride salts of substituted tryptamines
Belanger, Zachary S.,Chadeayne, Andrew R.,Golen, James A.,Manke, David R.,Pham, Duyen N. K.
, p. 615 - 620 (2021/10/14)
The crystal structures of the hydro chloride salts of nine substituted tryptamines, namely, 1-methyl trypt am mon ium chloride, C11H15N2 +·Cl-, (1), 2-methyl-1-phenyl trypt am mon ium chloride, C17H19N2 +·Cl-, (2), 5-meth oxy trypt am mon ium chloride, C11H15N2O+·Cl-, (3), 5-bromo trypt am mon ium chloride, C10H12BrN2 +·Cl-, (4), 5-chloro trypt am mon ium chloride, C10H12ClN2 +·Cl-, (5), 5-fluoro trypt am mon ium chloride, C10H12FN2 +·Cl-, (6), 5-methyl trypt am mon ium chloride, C11H15N2 +·Cl-, (7), 6-fluoro trypt am mon ium chloride, C10H12FN2 +·Cl-, (8), and 7-methyl trypt am mon ium chloride, C11H15N2 +·Cl-, (9), are reported. The seven tryptamines with N - H indoles, (3)-(9), show very similar structures, with N - H?Cl hydro gen-bonding networks forming two-dimensional sheets in the crystals. These sheets are combinations of R 4 2(8) and R 4 2(18) rings, and C 2 1(4) and C 2 1(9) chains. Substitution at the indole N atom reduces the dimensionality of the hydro gen-bonding network, with com pounds (1) and (2) demonstrating one-dimensional chains that are a combination of different rings and parallel chains.