27126-20-1

Basic information

• Product Name: Benzene, (3-azidopropyl)-
• CAS NO: 27126-20-1
• Molecular Formula: C9H11N3
• Molecular Weight: 161.206
• Mol File: 27126-20-1.mol
• Article Data: 54

Chemical Properties

• CAS DataBase Reference: Benzene, (3-azidopropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (3-azidopropyl)-(27126-20-1)
• EPA Substance Registry System: Benzene, (3-azidopropyl)-(27126-20-1)

Safety Data

• Hazardous Substances Data: 27126-20-1(Hazardous Substances Data)

Upstream product

• 4119-41-9 1-iodo-3-phenylpropan 
• 300-57-2 allylbenzene 
• 61124-61-6 3-phenylpropanal p-tosylhydrazone 
• 1082742-89-9 3-phenylpropyl quinoline-8-sulfonate 
• 112471-51-9 2-(3-phenylpropoxy)tetrahydro-2H-pyran 
• 122-97-4 3-Phenyl-1-propanol 
• 601488-42-0 5-dimethylamino-naphthalene-1-sulfonic acid 3-phenyl-propyl ester 
• 104-52-9 phenylpropyl chloride 
• 69804-99-5 3-phenylpropanol methanesulfonate 
• 637-59-2 1-Bromo-3-phenylpropane 

Downstream Products

• 30684-05-0 3-phenylpropylamine hydrochloride 
• 1133862-76-6 2-[1-(3-phenylpropyl)-1H-1,2,3-triazol-4-yl]propan-2-ol 
• 1204429-02-6 1-benzyl-1'-(3-phenylpropyl)-1H,1'H-4,4'-bi-1,2,3-triazole 
• 1204429-06-0 1-octyl-1'-(3-phenylpropyl)-1H,1'H-4,4'-bi-1,2,3-triazole 
• 14773-47-8 2-phenyl-N-(3-phenylpropyl)acetamide 
• 70622-91-2 1-phenyl-3-(3-phenylpropyl)urea 

Relevant articles and documents

Chemoselective triazole-phosphonamidate conjugates suitable for photorelease

Herein, we describe a new method for the conjugation of azide-containing target compounds that can be readily released as amines by irradiation with near UV light. This concept is based on a two-step protocol employing the chemoselective CuAAC and Staudinger-phosphonite reactions to deliver photo-cleavable phosphonamidate conjugates in high yields starting from 2-nitrobenzyl substituted phosphonites.

Interrupted CuAAC-Thiolation for the Construction of 1,2,3-Triazole-Fused Eight-Membered Heterocycles from O-/N-Propargyl derived Benzyl Thiosulfonates with Organic Azides

A copper(I)-catalyzed interrupted click-sulfenylation of O-/N-propargyl benzyl thiosulfonates with organic azides has been disclosed. The unified CuAAC-thiolation provides a wide range of triazole-fused eight-membered heterocycles in good to high (51–94%) yields under mild reaction conditions. Moreover, a three-component reaction is also achieved involving O-/N-propargyl benzyl thiosulfonates, benzyl bromide, and sodium azide to deliver fused-triazoles in 61–74% yields. From a synthetic point of view, the present protocol has been demonstrated at gram-scale reactions. A plausible mechanism is also proposed based on experimental results and control experiments. (Figure presented.).

A click-based modular approach to introduction of peroxides onto molecules and nanostructures

Copper-promoted azide/alkyne cycloadditions (CuAAC) are explored as a tool for modular introduction of peroxides onto molecules and nanomaterials. Dialkyl peroxide-substituted alkynes undergo Cu(i)-promoted reaction with azides in either organic or biphas

Iridium-catalyzed orthogonal and regioselective synthesis of triazole disulfides in aqueous media under mild conditions

An orthogonal and regioselective synthesis of triazole disulfides in aqueous media under mild conditions has been developed. This simple and practical approach is environment-friendly and compatible with oxygen/water and various complex biological media.