27143-81-3Relevant articles and documents
One-pot copper(I)-catalyzed synthesis of 3,5-disubstituted isoxazoles
Hansen, Trond V.,Wu, Peng,Fokin, Valery V.
, p. 7761 - 7764 (2007/10/03)
3,5-Disubstituted isoxazoles are obtained in good yields by a convenient one-pot, three-step procedure utilizing a regioselective copper(I)-catalyzed cycloaddition reaction between in situ generated nitrile oxides and terminal acetylenes. Most functional
Diastereoselective [3+2] cycloadditions of a camphor-derived chiral N- acryloylhydrazide with nitrile oxides: The preparation of optically pure δ2-isoxazolines
Yang, Kung-Shuo,Lain, Jung-Chaing,Lin, Chun-Hui,Chen, Kwunmin
, p. 1453 - 1456 (2007/10/03)
Reaction of a novel chiral N-acryloylhydrazide with various nitrile oxides proceeded smoothly to afford the cycloadduct with high diastereoselectivity (99:1). The auxiliary can be easily removed from the cycloadducts under mild conditions. (C) 2000 Elsevier Science Ltd.
Cycloadditions, 18: 5-Aminoisoxazoles by Cycloaddition of Nitrile Oxides to Ynamines
Himbert, Gerhard,Kuhn, Hildegard,Barz, Michael
, p. 403 - 407 (2007/10/02)
Ten differently substituted ynamines 1a-j react with five nitrile oxides 3a-e to give the 5-aminoisoxazoles 4a-z.The stannyl-substituted ynamine 1k furnishes the same compounds (e.g. 4a-d) by reaction with the hydroximoyl chlorides 2a-d.Two representatives of 4 - b and p - can be transformed into the corresponding 1-azirine-3-carboxamides 6a and b.