2715-68-6

Usage

Uses

Used in Cancer Research and Treatment:
9-Ethyl Adenine is used as a cytotoxic agent for cancer cell manipulation through the manipulation of osmium arene complexes. This application is significant in the development of potential cancer treatments, as it targets and destroys cancer cells.
Used in Microbial Determination of Niacin:
9-Ethyl Adenine is utilized in the determination of niacin in microbial systems. This application aids in understanding the role of niacin in various biological processes and its importance in maintaining overall health.
Used in Research on Heredity, Virus Diseases, and Cancer:
9-Ethyl Adenine plays a vital role in research related to heredity, virus diseases, and cancer. Its involvement in nucleic acids and coenzymes makes it an essential component in the study of genetic information, viral mechanisms, and cancer development.

InChI:InChI=1/C7H9N5/c1-2-12-4-11-5-6(8)9-3-10-7(5)12/h3-4H,2H2,1H3,(H2,8,9,10)

Upstream product

• 163084-89-7 benzyl (2S,4S)-2-(tert-butyl)-4-isobutyl-5-oxooxazolidine-3-carboxylate 
• 316352-92-8 9-(2-iodoethyl)-N⁶-(2-methylpropionyl)adenine 
• 75-03-6 ethyl iodide 
• 73-24-5 7H-purin-6-ylamine 

Downstream Products

• 107287-18-3 9-ethyl-1-<(2-hydroxymethyl)benzyl>adenine hydrobromide 
• 107312-07-2 9-ethyl-1-(2-methylbenzyl)adenine hydrobromide 
• 107287-19-4 9-ethyl-7-(2-methylbenzyl)adeninium bromide 
• 107287-10-5 9-ethyl-1-(3-hydroxypropyl)adenine hydrobromide 
• 5427-23-6 9-Ethylpurine 
• 5462-86-2 6-chloro-9-ethyl-9H-purine 
• 7280-85-5 6-benzamido-N⁹-ethylpurine 
• 561321-16-2 3-ethyl-3H-8-methyl-imidazo[2,1-i]purine 
• 561321-13-9 3-ethyl-3H-7-methyl-imidazo[2,1-i]purine 
• 107287-30-9 9-ethyl-N-(2-methylbenzyl)adenine 
• 107287-29-6 9-ethyl-N-<(2-hydroxymethyl)benzyl>adenine hydrobromide 
• 83026-89-5 9-ethyl-6-phenyl-9H-purine 
• 83026-97-5 6-(phenylthio)-9-ethylpurine 
• 1114376-04-3 (η6-biphenyl)(6-methylpicolinato)(9-ethyladenine-N1)osmium(II)(1+) 

Relevant academic research and scientific papers

Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleic acid bases in their side chains

N-(2-Iodoethyl) and N-(3-iodopropyl)pyrimidines and purines undergo stereoselective conjugate radical addition with an optically active oxazolidinone acceptor to give syn-adducts that can be converted into pyrimidine and purine amino acids.

Synthesis and binding behavior of an artificial receptor based on 'upper rim' functionalized calix[5]arene

A new calix[5]arene possessing two benzoic acid moieties was synthesized as an artificial receptor and its ability of binding to a variety of amine guests was investigated. The structures of the complexes with the mines were proposed by the molecular mechanics calculation using MacroModel V. 4.0.

Heterocyclic Ambident Nucleophiles. III* The Alkylation of Sodium Adenide

The alkylation of sodium adenide in HCONMe2 (30 deg) with various alkylating agents was analysed by 1H n.m.r. spectroscopy.Widely varying N3:N7:N9 alkylation patterns were observed, depending on the alkylating agent.These patterns are interpreted in terms of the electrostatic, thermodynamic and steric factors involved in the different SN2 transition states appropriate to each alkylating agent.Hydrogen bonding association between the 6-amino group and certain carbonyl containing alkylating agents is proposed to explain the enhancedN7-alkylation in some cases.Support for this latter proposal was obtain from a comparison of the adenine alkylation results with the corresponding alkylation patterns of 6-pivaloylamino- and 6-chloro-purine.