271583-72-3

Basic information

• Product Name: N-benzyl amino-(3-methylphenyl)acetonitrile
• Synonyms: N-benzyl amino-(3-methylphenyl)acetonitrile
• CAS NO: 271583-72-3
• Molecular Weight: 236.316
• Mol File: 271583-72-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-benzyl amino-(3-methylphenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl amino-(3-methylphenyl)acetonitrile(271583-72-3)
• EPA Substance Registry System: N-benzyl amino-(3-methylphenyl)acetonitrile(271583-72-3)

Safety Data

• Hazardous Substances Data: 271583-72-3(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 143-33-9 sodium cyanide 
• 620-23-5 m-tolyl aldehyde 
• 100-46-9 benzylamine 

Downstream Products

• 271583-30-3 benzylamino-m-tolyl-acetic acid 
• 53519-82-7 2-amino-2-(3-methylphenyl)acetic acid 
• 271583-50-7 2-benzylamino-2-m-tolyl-acetamide 

Relevant articles and documents

Asymmetric addition of trimethylsilylcyanide to N-benzylimines catalyzed by recyclable chiral dimeric V(V) salen complex

Chiral dimeric vanadium (V) salen complex (10 mol%) derived from 5,5-Methylene di-[(S,S)-{N-(3-tert-butyl salicylidine)-N′-(3′,5′-di-tert-butyl salicylidene)]-1,2-cyclohexanediamine] with vanadyl suphate followed by auto oxidation was used as efficient catalyst for enantioselective Strecker reaction of N-benzylimines with TMSCN at -30 °C. Excellent yield (92%) of α-aminonitrile and high chiral induction was achieved (ee up to 94%) in case of 2-methoxy substituted N-benzylimines in 10 h. The catalytic system worked well up to four cycles with retention of enantioselectivity.