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1,2-Phenylenedioxydiacetonitrile is an organic compound characterized by its off-white solid appearance. It is known for its unique chemical structure, which features a phenylene ring with a dioxydiacetonitrile group attached. This structure endows the compound with specific properties that make it suitable for various applications in different industries.

27165-64-6

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27165-64-6 Usage

Uses

Used in Pharmaceutical Industry:
1,2-Phenylenedioxydiacetonitrile is used as a key intermediate in the synthesis of β-adrenergic stimulants. These stimulants are essential in the treatment of various medical conditions, such as asthma, chronic obstructive pulmonary disease (COPD), and heart-related issues. The compound's unique structure allows for the development of potent and effective medications that can help manage these conditions.
In the preparation of β-adrenergic stimulants, 1,2-Phenylenedioxydiacetonitrile serves as a crucial building block. Its chemical properties enable the formation of the desired active pharmaceutical ingredients (APIs) with the necessary potency and selectivity. This application highlights the importance of 1,2-Phenylenedioxydiacetonitrile in the development of life-saving drugs and its contribution to the pharmaceutical industry.
Overall, 1,2-Phenylenedioxydiacetonitrile is a versatile compound with significant applications in the pharmaceutical industry, particularly in the development of β-adrenergic stimulants. Its unique chemical structure and properties make it an essential component in the synthesis of these vital medications, further emphasizing its importance in the field of drug development and healthcare.

Check Digit Verification of cas no

The CAS Registry Mumber 27165-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,1,6 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 27165-64:
(7*2)+(6*7)+(5*1)+(4*6)+(3*5)+(2*6)+(1*4)=116
116 % 10 = 6
So 27165-64-6 is a valid CAS Registry Number.

27165-64-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (O-Phenylenedioxy)diacetonitrile

1.2 Other means of identification

Product number -
Other names 2-[2-(cyanomethoxy)phenoxy]acetonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27165-64-6 SDS

27165-64-6Relevant academic research and scientific papers

Cytosine analogues from substituted acetonitriles via Thorpe condensation

Barkin, Julia L.,Faust Jr., Marcus D.,Trenkle, William C.

, p. 3333 - 3335 (2007/10/03)

(Matrix presented) A Thorpe condensation is the key bond construction in a rapid and efficient synthesis of substituted cytosine derivatives from readily available starting materials.

Synthesis of dioxigenated systems. Preparation of homologues of 1,4-benzodioxin as calcium antagonists

Sánchez,Pujol,Guillaumet,Massingham,Monteil

, p. 11 - 19 (2007/10/03)

A new compound (9), homologue of 1,4-benzodioxin, has been prepared and tested as calcium antagonist. Additionally, the intermediates 12 and 13 with structure of aminodiol, were also evaluated as anticalcium agents. All of them showed a moderate anticalci

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