2719-28-0Relevant academic research and scientific papers
General Synthetic Route to Malonamic Acids and 3-Thiomalonamic Acids. Amidations and Thioamidations of α Anions of Carboxylate Salts with Alkyl and Aryl Isocyanates and Isothiocyanates
Krapcho, A. Paul,Stephens, W. P.
, p. 1106 - 1109 (2007/10/02)
Treatment of α anions of carboxylate salts 2 with alkyl or aryl isocyanates and isothiocyanates leads to substituted malonamic acids (4, X=O) and 3-thiomalonamic acids (4, X=S), respectively.Lithium naphthalenide is utilized as the base in the formation o
