2719-73-5

Basic information

• Product Name: Benzaldehyde, 2-pyridinylhydrazone
• CAS NO: 2719-73-5
• Molecular Formula: C12H11N3
• Molecular Weight: 197.239
• Mol File: 2719-73-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-pyridinylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-pyridinylhydrazone(2719-73-5)
• EPA Substance Registry System: Benzaldehyde, 2-pyridinylhydrazone(2719-73-5)

Safety Data

• Hazardous Substances Data: 2719-73-5(Hazardous Substances Data)

Upstream product

• 109-09-1 2-chloropyridine 
• 100-52-7 benzaldehyde 
• 5281-18-5 benzaldehyde, hydrazone 
• 4930-98-7 pyrid-2-ylhydrazine 

Downstream Products

• 778-65-4 3-phenyl-[1,2,4]triazolo[4,3-a]pyridine 
• 1293979-78-8 2-benzylidene-6-bromo-3,3-difluoro-2,3-dihydro[1,2,4,3]triazaborolo[4,5-a]pyridin-2-ium-3-uide 
• 16054-93-6 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one 

Relevant articles and documents

Toward Hypoxia-Selective Rhenium and Technetium Tricarbonyl Complexes

With the aim of preparing hypoxia-selective imaging and therapeutic agents, technetium(I) and rhenium(I) tricarbonyl complexes with pyridylhydrazone, dipyridylamine, and pyridylaminocarboxylate ligands containing nitrobenzyl or nitroimidazole functional g

Solvatochromic triazaborolopyridinium probes toward ultra-sensitive trace water detection in organic solvents

A series of triazaborolopyridiniums (TBP) has been synthesized by varying electron-tunning substituents. The TBP derivatives with electron-withdrawing groups, including cyano, and nitro moieties, exhibited solvatochromic properties due to the internal cha

Synthesis method for 1,2,4-triazolopyridine derivative

The invention provides a novel synthesis method for a 1,2,4-triazolopyridine derivative. According to the invention, the 1,2,4-triazolopyridine derivative can be obtained by taking a 2-pyridine hydrazone derivative and sodium hypochlorite as main synthesis raw materials through a reaction for 1-24 hours in an organic solvent at a temperature of 0-100 DEG C. The invention provides a synthetic method which is good in atom economy, mild in reaction conditions, simple and convenient to operate and easy to be controlled for the 1,2,4-triazolopyridine derivative.

1H-[1,2,4]Triazolo[4,3-a]pyridin-4-ium and 3H-[1,2,4]triazolo[4,3-a]quinolin-10-ium derivatives as new intercalating agents for DNA

Two new cationic DNA intercalators, 3-phenyl-1-(6-phenylpyridin-2-yl)-1H-[1,2,4]triazolo[4,3-a]pyridin-4-ium (1a)+ and 1-phenyl-3-(6-phenylpyridin-2-yl)-3H-[1,2,4]triazolo[4,3-a]quinolin-10-ium (1b)+, were synthesized from 2-chloropyridine and 2-chloroquinoline, respectively, in a four-step procedure. Generation of the hydrazine, followed by condensation with an aldehyde to give a hydrazone and subsequent Buchwald-Hartwig amination gave a mixture of E- and Z-configured N,N-functionalized hydrazones. Finally, oxidative cyclisation gave rise to the formation of the cationic DNA intercalators, whose molecular structures were determined by single-crystal X-ray diffraction analysis of the hexafluorophosphate and tribromide salt of (1a)+ and (1b)+, respectively. The intercalative binding of (1a)PF6 and (1b)PF6 to ctDNA was confirmed by means of UV, CD and luminescence spectroscopy, determination of the DNA melting temperature and by rheology measurements.