Welcome to LookChem.com Sign In|Join Free


  • or


Post Buying Request

27200-12-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • High Quality 99% 4H-1-Benzopyran-4-one,2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-, (2R,3R)- 27200-12-0 ISO Producer

    Cas No: 27200-12-0

  • USD $ 0.1-0.1 / Gram

  • 1 Gram

  • 100 Metric Ton/Year

  • Xi'an Xszo Chem Co., Ltd.
  • Contact Supplier

27200-12-0 Usage


Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound found in significant quantities in certain Asian plant species, particularly Hovenia dulcis. This plant has been utilized in traditional Chinese medicine for centuries as a remedy for alcohol poisoning and hangovers. DHM is also commercially available as a supplement, often marketed to alleviate hangover symptoms due to its capacity to lower blood alcohol levels and its potential hepatoprotective properties. Research has demonstrated that DHM possesses a range of health benefits, including antimicrobial, anti-inflammatory, antioxidative, anticancer, and lipid and glucose metabolism-regulatory activities. Moreover, it mediates cell death with minimal adverse effects on normal cells and has been shown to offer substantial hepatoprotective effects, particularly in the context of alcohol-induced and other liver diseases.


Used in Pharmaceutical Applications:
Dihydromyricetin is used as a supplement for treating hangovers, attributed to its ability to reduce blood alcohol levels and its hepatoprotective properties.
Used in Anticancer Applications:
Dihydromyricetin is used as an anticancer agent, particularly in studying its antitumor activity against liver cancer cells.
Used in Metabolic Regulation:
Dihydromyricetin is used as a regulator for lipid and glucose metabolism, potentially benefiting individuals with related health conditions.
Used in Antimicrobial Applications:
Dihydromyricetin is used as an antimicrobial agent, leveraging its natural ability to combat harmful microorganisms.
Used in Anti-inflammatory Applications:
Dihydromyricetin is used as an anti-inflammatory agent, potentially aiding in the reduction of inflammation in the body.
Used in Antioxidative Applications:
Dihydromyricetin is used as an antioxidant, helping to neutralize harmful free radicals and protect cells from oxidative damage.
Used in Hepatoprotective Applications:
Dihydromyricetin is used as a hepatoprotective agent, providing significant protection to the liver, especially in cases of alcohol-induced and other liver diseases.
Used in Cell Death Mediation:
Dihydromyricetin is used in the mediation of cell death, particularly in the context of cancer treatment, where it can target cancerous cells with minimal adverse effects on normal cells.


Dihydromyricetin (DHM) relieves alcohol toxicity and prevents intoxication by limiting the absorption of alcohol in the gastrointestinal tract and promoting the metabolisation of alcohol in the liver. DHM is a promising compound for kidney protection, liver protection, and neurological protection when drinking alcohol.DHM benefits can include things like:relieve hangoverrelieve anxietycardioprotective propertiesprotect the liver

Biochem/physiol Actions

Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity, found to have anti-alcohol intoxication effects. Its anti-alcohol effects appear to be by its actions as a positive modulator of GABA-A receptors at the benzodiazepine site.

Side effects

Dihydromyricetin has been used in Asia for thousands of years as a hangover cure and anti-intoxication medicine and is considered safe for humans even in massive doses.In a DHM toxicity study, researchers failed to find any side-effects while giving mice massive doses of up to 22g/kg body weight.Acute toxicity tests showed that a single dose of oral SHE up to 22 g/kg did not result in any death or toxic side effects in mice during 14 days'observation.Conversions from rat to human pharmacology can be estimated using the HED ratio of 16%, giving DHM a safe upper limit dosage of 15.68g for a 70kg person.

Check Digit Verification of cas no

The CAS Registry Mumber 27200-12-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27200-12:
70 % 10 = 0
So 27200-12-0 is a valid CAS Registry Number.

27200-12-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Sigma

  • (SML0295)  Dihydromyricetin  ≥98% (HPLC)

  • 27200-12-0

  • SML0295-5MG

  • 776.88CNY

  • Detail
  • Sigma

  • (SML0295)  Dihydromyricetin  ≥98% (HPLC)

  • 27200-12-0

  • SML0295-25MG

  • 3,149.64CNY

  • Detail
  • Sigma-Aldrich

  • (42866)  Dihydromyricetin  analytical standard

  • 27200-12-0

  • 42866-10MG

  • 1,547.91CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name (+)-dihydromyricetin

1.2 Other means of identification

Product number -
Other names rac-ampelopsin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27200-12-0 SDS

27200-12-0Relevant articles and documents

Heterocycles. XXV. Sodium Borohydride Reduction of Flavanonols

Li, Shaoshun,Onda, Masayuki,Kagawa, Hitoshi,Kawase, Hiromi,Iguchi, Mieko,Harigaya, Yoshihiro

, p. 2029 - 2035 (2007/10/02)

Solvent effects on the stereochemistry in the sodium borohydride reduction of (+/-)-flavanonols have been examined.The effects observed for the (+/-)-flavanonols with 5-OMe in 2-propanol, dioxane and methanol are explainable by the differences between the steric interactions inherent in the product-like transition states A and B.It has been also found that 5-OAc peculiarly affects the stereochemistry in the reduction to produce the (+/-)-catechin-type compounds in a one-pot process.The solvent and temperature effects are examined using a model analogous to the above.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)


What can I do for you?
Get Best Price

Get Best Price for 27200-12-0