272113-90-3 Usage
Chemical Class
Aziridinecarboxamides
Chirality
Chiral compound with a 2S,3R configuration
Medical Use
Anti-cancer drug used in the treatment of various types of cancer
Types of Cancer Treated
Breast, bladder, ovarian, and others
Mechanism of Action
DNA Damage: Thiotepa damages the DNA of cancer cells
Prevention of Cell Multiplication: Damaging DNA prevents cancer cells from multiplying
Induction of Cell Death: Ultimately leads to the death of cancer cells
Functional Group
2-propenyl group
Properties Conferred by Functional Group
Alkylating Agent: Allows the compound to act as an alkylating agent
Anti-tumor Properties: Contributes to its anti-tumor properties
Administration
Intravenous infusion
Efficacy
Considered effective in cancer treatment
Importance
Regarded as an important drug in cancer treatment
Check Digit Verification of cas no
The CAS Registry Mumber 272113-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,2,1,1 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 272113-90:
(8*2)+(7*7)+(6*2)+(5*1)+(4*1)+(3*3)+(2*9)+(1*0)=113
113 % 10 = 3
So 272113-90-3 is a valid CAS Registry Number.
272113-90-3Relevant academic research and scientific papers
A new selective synthesis of the Ile-allo-Thr-Gly tripeptide fragment of lysobactin.
Armaroli,Cardillo,Gentilucci,Gianotti,Tolomelli
, p. 1105 - 1107 (2007/10/03)
[formula: see text] trans-Aziridine-2-carboxylic acid derivatives are useful intermediates for the synthesis of threonine or allo-threonine through ring expansion and SN2 displacement, respectively. We describe here the preparation of the Ile-allo-Thr-Gly 11 fragment of Lysobactin via the aziridine 9 intermediate.
