27224-48-2Relevant academic research and scientific papers
N-Heterocyclic Carbene-Catalyzed β-Indolylation of α-Bromoenals with Indoles
Sun, Shaofa,Lang, Ming,Wang, Jian
, p. 5704 - 5708 (2019)
An unprecedented example of NHC-catalyzed β-indolylation of α-bromoenals with indoles has been developed. This concise protocol features several advantages (mild reaction conditions, broad substrate scope) and constructs synthetically useful building blocks, namely β-biaryl methylene esters. Notably, the β-biaryl methylene-type fragment is widely found in natural products or pharmaceuticals. (Figure presented.).
