27241-90-3Relevant academic research and scientific papers
N-Aminations of Benzylamines and Alicyclic Amines with Nitrosoarenes to Hydrazones and Hydrazides
Jana, Chandan K.,Purkait, Anisha
, p. 2687 - 2696 (2019/06/19)
Unlike other alkylamines, benzylamines upon reaction with a nitrosoarene undergo oxidation to the corresponding imines. A direct amination of benzylamines, which was difficult to achieve due to its facile oxidation, to the corresponding hydrazones is reported. A wide variety of benzylamines and N-heterocycles were reacted with nitrosoarenes to provide structurally diverse hydrazones and hydrazides, respectively. Moreover, the direct N-amination reaction was applied to the one-pot synthesis of triazoles.
Antimalarial activity of small-molecule benzothiazole hydrazones
Sarkar, Souvik,Siddiqui, Asim A.,Saha, Shubhra J.,De, Rudranil,Mazumder, Somnath,Banerjee, Chinmoy,Iqbal, Mohd S.,Nag, Shiladitya,Adhikari, Susanta,Bandyopadhyay, Uday
, p. 4217 - 4228 (2016/07/11)
We synthesized a new series of conjugated hydrazones that were found to be active against malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones concentration-dependently chelated free iron and offered antimalarial activity. Upo
Synthesis, crystal structure, optical and electrochemical properties of novel diphenylether-based formazan derivatives
Turkoglu, Gulsen,Berber, Halil,Kani, Ibrahim
supporting information, p. 2728 - 2740 (2015/04/14)
In this study, formazans 5a-5h were synthesized by coupling the reactions of substituted phenylhydrazone compounds 3a-3h with diazonium salt of 4-chloro-2-phenoxybenzenamine (4). The substituted phenylhydrazones 3a-3h were obtained from the condensation o
A novel chemoselective synthesis of 3H-spiro[isobenzofuran-1,3'-pyrazole] derivatives by oxidative cleavage of their corresponding dihydroindeno[1,2-c]pyrazoles
Mohammadizadeh, Mohammad Reza,Basti, Fatemeh
, p. 1171 - 1176 (2015/06/02)
Abstract This paper reports a new and simple procedure for the synthesis of 3H-spiro[isobenzofuran-1,3'-pyrazole] derivatives by reacting 1-benzylidene-2-phenylhydrazine derivatives with ninhydrin in acetic acid medium at room temperature followed by oxidative cleavage of their corresponding dihydroindeno[1,2-c]pyrazoles. 1-Benzylidene-2-phenylhydrazine derivatives were prepared via the reaction between phenylhydrazine and benzaldehyde derivatives. Easy procedure, mild reaction conditions, high yields in short reaction times, availability of starting materials, and no formation of by-product are the advantages of this approach.
A new route to substituted pyrimido[5,4-e]-l,2,4-triazine-5,7(1H,6H)-diones and facile extension to 5,7(6H,8H) isomers
Turbiak, Anjanette J.,Showalter, H. D. Hollis
experimental part, p. 4022 - 4026 (2010/03/30)
A new route to substituted pyrimido[5,4-e]-l,2,4-triazine-5,7(lH,6H)-diones is outlined. The synthesis proceeds via preformed hydrazone intermediates, which are then condensed with an activated chlorouracil to build up the entire molecular framework, foll
