272463-67-9Relevant academic research and scientific papers
An expedient synthesis of 2-(ω-carboxyalkyl)polyhydroxyisoflavones
Al-Maharik, Nawaf,Mutikainen, Ilpo,W?h?l?, Kristiina
, p. 411 - 416 (2000)
Derivatives of the isoflavones daidzein and genistein, carrying a carboxyalkyl attachment at C-2 were prepared by cyclization of unprotected 2,4,4'-trihydroxy- or 2,4,4',6-tetrahydroxydeoxybenzoin in the presence of a number of 1,ω-alkanedicarboxylic acid monoester monochlorides, K2CO3 and a phase-transfer catalyst in dry acetone. Hydrolysis under basic conditions of the resulting 2-(ω-alkoxycarbonylalkyl)isoflavones gives the title compounds, useful for developing RIA techniques for the analysis of the parent isoflavones.
