272775-65-2

Basic information

• Product Name: 3-(3',4'-dichlorophenyl)-3-buten-1-ol
• Synonyms: 3-(3',4'-dichlorophenyl)-3-buten-1-ol
• CAS NO: 272775-65-2
• Molecular Weight: 217.095
• Mol File: 272775-65-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(3',4'-dichlorophenyl)-3-buten-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3',4'-dichlorophenyl)-3-buten-1-ol(272775-65-2)
• EPA Substance Registry System: 3-(3',4'-dichlorophenyl)-3-buten-1-ol(272775-65-2)

Safety Data

• Hazardous Substances Data: 272775-65-2(Hazardous Substances Data)

Upstream product

• 191673-76-4 methyl 3-(3,4-dichlorophenyl)-3-butenoate 
• 50-00-0 formaldehyd 
• 41575-21-7 1,2-dichloro-4-(prop-1-en-2-yl)benzene 
• 1034183-25-9 3-(3,4-Dichloro-phenyl)-but-3-enoic acid 
• 18282-59-2 4-bromo-1,2-dichlorobenzene 
• 76334-36-6 3-bromobut-3-en-1-ol 
• 151169-75-4 3,4-dichlophenylboronic acid 

Downstream Products

• 1013097-83-0 3-(3,4-dichlorophenyl)-3-buten-1-yl methanesulfonate 
• 1186627-30-4 1,1-dimethylethyl (1R,6S)-6-(3,4-dichlorophenyl)-1-{[(methylsulfonyl)oxy]methyl}-3-azabicyclo[4.1.0]heptane-3-carboxylate 

Relevant articles and documents

NOVEL COMPOUNDS

The invention relates to compounds of formula (I), processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as serotonin (5-HT), dopamine (DA) and norepinephrine (NE), re-uptake inhibitors.

Formaldehyde Encapsulated in Zeolite: A Long-Lived, Highly Activated One-Carbon Electrophile to Carbonyl-Ene Reactions

Gaseous formaldehyde is extremely unstable and readily undergoes self-polymerization to a solid paraformaldehyde or disproportionation to methanol and formic acid in the presence of moisture. We disclose a simple method to stably store such a labile formaldehyde as a monomer in a nanoporous faujasite zeolite at 5 °C for at least 50 days without self-polymerization or disproportionation. The greater stability of formaldehyde encapsulated in zeolite was confirmed by 13C MAS NMR spectroscopy. Formaldehyde was not only stabilized within the zeolite cages but functioned as a powerful electrophile toward various olefins. Zeolite-encapsulated formaldehyde was proved to be a stable but highly reactive C1 reagent. Copyright

An efficient synthesis of enantiomerically pure 2-[(2R)-arylmorpholin- 2-yl]ethanols, key intermediates of tachykinin receptor antagonist

We report herein an efficient and practical synthetic method for the preparation of enantiomerically pure 2[(2R)-arylmorpholin-2-yl]ethanols 1a- d, key intermediates of tachykinin receptor antagonist. Sharpless catalytic asymmetric dihydroxylation of 4a-d was employed to introduce the required absolute stereochemistry, and cyclization of 7a-d was accomplished by the Mitsunobu reaction.