272789-40-9Relevant articles and documents
Design and synthesis of an α,α-difluorophosphinate hapten for antibody-catalyzed hydrolysis of organophosphorus nerve agents
Vayron, Philippe,Renard, Pierre-Yves,Valleix, Alain,Mioskowski, Charles
, p. 1050 - 1063 (2007/10/03)
In a new approach to the safe neutralization of organophosphorus chemical weapons, we designed a hapten to elicit catalytic antibodies with phosphatase activity. Here we report the synthesis of this α,α- difluorophosphinate hapten 6. Various methods for t