62740-39-0

Upstream product

• 36103-43-2 diethyl benzylphosphonite 
• 644-97-3 Dichlorophenylphosphine 
• 64-17-5 ethanol 
• 5284-12-8 ethyl chloro(phenyl)phosphinate 

Downstream Products

• 25881-42-9 (1-Benzylamino-propyl)-phenyl-phosphinic acid 
• 25881-44-1 (1-Benzylamino-pentyl)-phenyl-phosphinic acid 
• 25881-45-2 (Benzylamino-phenyl-methyl)-phenyl-phosphinic acid 
• 25881-43-0 N-Benzyl-α-aminobutanphenylphosphinsaeure 
• 272789-39-6 Ethyl {1-hydroxy-[2-nitro-5-(tetrahydropyran-2-yloxy)-phenyl]-methyl}-phenylphosphinate 
• 272789-40-9 Ethyl (1-hydroxy-{5-[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-propoxy]-2-nitrophenyl}-methyl)-phenylphosphinate 
• 272789-34-1 Ethyl [1-hydroxy-1-(6-nitro-1,3-benzodioxol-5-yl)-methyl]-phenylphosphinate 
• 76734-43-5 (3-Acetoxy-3-cyano-propyl)-phenylphosphinic acid ethyl ester 
• 25881-50-9 (1-Amino-pentyl)-phenyl-phosphinic acid 
• 26067-67-4 (1-Amino-butyl)-phenyl-phosphinic acid 
• 25881-49-6 α-aminopropane(phenyl)phosphinic acid 

Relevant academic research and scientific papers

2, 4, 6-trimethyl benzoyl phenyl phosphinic acid ethyl ester preparation method

The invention relates to a preparation method of 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate, and in particular relates to a method for preparing 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate through the steps of carrying out substitution condensation reaction on dichlorophenyl phosphine and ethanol to obtain an intermediate; performing condensation reaction on the intermediate and 2,4,6-trimethyl benzaldehyde under an alkaline condition, and finally performing oxidation by using an oxidant under catalysis of a catalyst. The preparation process of 2,4,6-trimethyl benzoyl phenyl ethyl phosphonate, disclosed by the invention, has the advantages as follows: the influences of an acidic medium on the intermediate can be avoided; the requirements of the condensation reaction between 2,4,6-trimethyl benzaldehyde and phenyl ethyl hypophosphite for reaction equipment can be reduced; meanwhile, the reaction yield can be ensured; the preparation process is simple in operation and is suitable for industrial production.

Process for preparing monoalkyl phosphonites

The invention relates to a process for preparing monoalkyl phosphonites of the formula I STR1 where R1 is (C1 -C16)-alkyl, cyclohexyl, cyclopentyl, or phenyl, each of which can also be substituted by halogen, (C1 -C6)-alkyl, (C1 -C6)-alkoxy or dialkylamino groups and R2 is (C1 -C8)-alkyl, which comprises reacting dichlorophosphines of the formula (II) where R1 has the meaning given above, with alcohols of the formula (III) where R2 has the meaning given above, the molar ratio of dichlorophosphine/alcohol being 1:3 to 1:20, and then, as soon as the content of ionic chlorine in the reaction mixture is 50-75% of the theoretical total chlorine content of the reaction mixture, reacting the mixture with ammonia.

ORGANOPHOSPHORUS CHEMISTRY. 2. THE REDUCTION OF QUINQUEVALENT PHOSPHORUS TO THE TRIVALENT STATE

Phosphoryl and phosphonyl chlorides are reduced conveniently to the monobasic acid forms of the corresponding phosphorous and phosphonous acids by the use of sodium borohydride dispersed in dioxane.