2732-80-1

Usage

Uses

Used in Chemical Synthesis:
3-Bromo-4-chloroanisole is used as a synthetic intermediate for the production of various organic compounds. Its unique structure allows it to be a key component in the synthesis of complex molecules.
Used in the Synthesis of N-heterocycle-fused Phenanthridines:
3-Bromo-4-chloroanisole is used as a starting material for the synthesis of N-heterocycle-fused phenanthridines, which are blue-emitting luminophores. These luminophores have potential applications in the development of advanced materials for optoelectronic devices, such as organic light-emitting diodes (OLEDs) and other display technologies.
Used in the Preparation of Indoles:
3-Bromo-4-chloroanisole is also utilized in the preparation of indoles, specifically through a Pd-catalyzed cascade process. Indoles are important structural motifs found in numerous biologically active compounds, including pharmaceuticals, agrochemicals, and natural products. The synthesis of indoles using 3-bromo-4-chloroanisole can lead to the development of new and innovative indole-based molecules with potential applications in various industries.

InChI:InChI=1/C7H6BrClO/c1-10-5-2-3-7(9)6(8)4-5/h2-4H,1H3

Upstream product

• 2401-24-3 2-chloro-5-methoxyaniline 
• 13659-24-0 3-bromo-4-chlorophenol 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 96-96-8 4-methoxy-2-nitroaniline 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 50586-69-1 2,3,6-tribromo-4-chloro-phenol 

Downstream Products

• 939771-49-0 1-chloro-2-(4-fluorophenoxy)-4-methoxybenzene 
• 1227188-08-0 2-chloro-N-(2,6-diisopropylphenyl)-5-methoxyaniline 
• 1259658-97-3 1,2-diphenyl-5-methoxy-1H-indole 
• 6280-89-3 2-chloro-5-methoxybenzoic acid 
• 1331753-60-6 (2-(2-chloro-5-methoxyphenoxy)phenyl)(phenyl)methanone 
• 1331753-37-7 7-methoxy-11-phenyldibenzo[b,f][1,4]oxazepine 
• 1350629-01-4 1-phenyl-2-(4-N,N-dimethylamino-phenyl)-1H-5-methoxy-benzo[d]imidazole 
• 1350629-08-1 5-methoxy-1,2-diphenyl-1H-benzo[d]imidazole 
• 1771-19-3 3-methoxy-10H-phenothiazine 
• 1599474-18-6 3-(2-chloro-5-methoxybenzyl)benzo[b]thiophene 
• 623-12-1 4-chloromethoxybenzene 
• 1354787-28-2 5-chloro-4-(6-chloro-2'-fluoro-4-iodobiphenyl-3-yloxy)-N-(2,4-dimethoxybenzyl)-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1354787-27-1 5-chloro-4-(6-chloro-2'-fluoro-4-(pyridazin-4-yl)biphenyl-3-yloxy)-N-(2,4-dimethoxybenzyl)-2-fluoro-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide 
• 1354786-50-7 5-Chloro-4-[(6-chloro-2'-fluoro-4-pyridazin-4-ylbiphenyl-3-yl)oxy]-2-fluoro-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide 

Relevant academic research and scientific papers

ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

A compound of Formula (I) or a pharmaceutically acceptable salt thereof is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

Induction of Axial Chirality in 8-Arylquinolines through Halogenation Reactions Using Bifunctional Organocatalysts

The enantioselective syntheses of axially chiral heterobiaryls were accomplished through the aromatic electrophilic halogenation of 3-(quinolin-8-yl)phenols with bifunctional organocatalysts that control the molecular conformations during successive halogenations. Axially chiral quinoline derivatives, which have rarely been synthesized in an enantioselective catalytic manner, were afforded in moderate-to-good enantioselectivities through bromination, and an analogous protocol also enabled enantioselective iodination. In addition, this catalytic reaction, which allows enantioselective control through the use of mono-ortho-substituted substrates, allowed the asymmetric synthesis of 8-arylquinoline derivatives bearing two different halogen groups in high enantioselectivities.