273377-11-0Relevant academic research and scientific papers
MITOTIC KINESIN INHIBITORS
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Page 208, (2008/06/13)
The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions
Overman rearrangement of γ-aryl crotyl alcohols: Effects of aryl substituents
Cho, Cheon-Gyu,Lim, Yeong-Kwan,Lee, Kang-Sang,Jung, In-Hak,Yoon, Moon-Yeong
, p. 1643 - 1650 (2007/10/03)
Various α,α'-methyl aryl allylic amines were synthesized from γ-aryl crotyl alcohols via thermal Overman rearrangement. Noteworthy is that the presence of the electron withdrawing groups at aryl group causes substantial increases in the reaction rates and
Ring closing metathesis of phenyl-substituted dienes
Bujard,Briot,Gouverneur,Mioskowski
, p. 8785 - 8788 (2007/10/03)
A series of phenyl-substituted heterodienes 2a-f and 6 was prepared and subjected to ring closing metathesis (RCM) to give differently phenyl- substituted dihydropyrroles and dihydrofuran.
