2736-08-5Relevant academic research and scientific papers
Nickel-catalyzed insertions of vinylidenes into Si-H bonds
Biswas, Sourish,Pal, Sudipta,Uyeda, Christopher
supporting information, p. 14175 - 14178 (2020/11/24)
A nickel-catalyzed reductive cyclization of 1,1-dichloroalkenyl silanes is reported. The products of this reaction are unsaturated five-or six-membered silacycles. Intermolecular variants are also described, providing access to trisubstituted vinyl silanes that are not accessible by alkyne hydrosilylation or sila-Heck-type processes. A variety of silanes can be utilized, including those that serve as nucleophilic partners in Hiyama cross-coupling reactions. Mechanistic studies using deuterium-labelled silanes are described. This journal is
Synthesis of unsaturated silyl heterocycles via an intramolecular silyl-heck reaction
Reid, William B.,McAtee, Jesse R.,Watson, Donald A.
, p. 3796 - 3803 (2019/10/11)
We report the synthesis of unsaturated silacycles via an intramolecular silyl-Heck reaction. Using palladium catalysis, silicon electrophiles tethered to alkenes cyclize to form five- and six-membered silicon heterocycles. The effects of alkene substitution and tether length on the efficiency and regioselectivity of the cyclizations are described. Finally, through the use of an intramolecular tether, the first examples of disubstituted alkenes in silyl-Heck reactions are reported.
