27370-93-0Relevant academic research and scientific papers
Widely applicable Pd-catalyzed trans-selective monoalkylation of unactivated 1,1-dichloro-1-alkenes and Pd-catalyzed second substitution for the selective synthesis of E or Z trisubstituted alkenes
Tan, Ze,Negishi, Ei-Ichi
, p. 762 - 765 (2006)
(Chemical Equation Presented) Double substitution: The first selective and widely applicable method for a step-wise alkylation of 1,1-dichloro-1-alkenes involving a cross-coupling double substitution using Pd-catalysis has been developed. This method provides an efficient and highly selective route for the synthesis of E or Z trisubstituted alkenes. dpephos = bis(o- diphenylphosphanylphenylether).
Direct preparation of vinyl halides from the corresponding ketones and acetyl halides
Moughamir, Khadija,Mezgueldi, Bouchra,Atmani, Aziz,Mestdagh, Helene,Rolando, Christian
, p. 59 - 62 (1999)
Vinyl chlorides and bromides are obtained in good yield from the corresponding ketones and acetyl halides in the presence of trifluoroacetic or trifluoromethanesulfonic acid. The Z isomer is selectively formed.
