27382-47-4

Upstream product

• 13501-67-2 N-(p-methoxyphenyl)anthranilic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 75-44-5 phosgene 
• 91-56-5 indole-2,3-dione 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 112934-63-1 1-(4Methoxyphenyl)-1H-indole-2,3-dione 

Downstream Products

• 27382-51-0 1-(4-methoxy-phenyl)-4-oxo-2-phenyl-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 1159215-95-8 N-(p-methoxyphenyl)-2,3-dipropyl-4-quinolone 

Relevant academic research and scientific papers

N-Arylation of Isatins. A Direct Route to N-Arylisatoic Anhydrides

The synthesis of N-arylisatoic anhydrides 3 has been accomplished by using a two-step process.The key reaction in the sequence is the direct N-arylation of isatin with an aryl bromide in the presence of cupric oxide.Subsequent oxidation of the resulting N

Substituted aminobenzoates, their preparation and use

Novel lower-alkyl 2-(hydroxyphenylamino)benzoates, useful as inhibitors of lipoxygenase, are of the formula STR1 wherein R is hydrogen, lower-alkyl or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and Alk is lower-alkyl. The compounds are prepared by de-etherification of the corresponding alkyl or benzyl ethers.

Substituted aminobenzamides and their use as agents which inhibit lipoxygenase activity

Novel 2-(hydroxyphenylamino)benzamides and oxidation products thereof, useful as inhibitors of lipoxygenase, are of the formulas STR1 wherein R is hydrogen, lower-alkyl, halo or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and N=Z is amino or substituted amino. The compounds of Formula I are prepared by de-etherification of the corresponding alkyl or benzyl ethers; and the compounds of Formula II are prepared by oxidation of the compounds of Formula I where R' is hydrogen and OH is in the 4-position.

3-[2-(4-Anisidino)phenyl]-1-phenyl-1-propiophenones and propanols

The invention relates to novel 1-(4-R1 O-phenyl)-2-(4-R2 -phenyl)-6-R3 -1,2,3,4-tetrahydroquinolines having anti-fertility and hypocholesterolemic activities, to their preparation, and to novel intermediates therefor.

Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds

The invention relates to novel 1-(4-R1 O-phenyl)-2-(4-R2 -phenyl)-6-R3 -1,2,3,4-tetrahydroquinolines having antifertility and hypocholesterolemic activities, to their preparation, and to novel intermediates therefor.