27384-09-4

Basic information

• Product Name: Phosphine oxide, acetyldiphenyl-
• Synonyms: Acetyl-(diphenyl)-phosphanoxid;Phosphine oxide,acetyldiphenyl;Acetyldiphenylphosphinoxid;acetyl-diphenyl-phosphine oxide
• CAS NO: 27384-09-4
• Molecular Formula: C14H13O2P
• Molecular Weight: 244.23
• Mol File: 27384-09-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 186-188 °C(Solv: ethanol (64-17-5))
• Boiling Point: 376.2±25.0 °C(Predicted)
• Density: 1.18±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Phosphine oxide, acetyldiphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, acetyldiphenyl-(27384-09-4)
• EPA Substance Registry System: Phosphine oxide, acetyldiphenyl-(27384-09-4)

Safety Data

• Hazardous Substances Data: 27384-09-4(Hazardous Substances Data)

Upstream product

• 4020-99-9 diphenylphosphinous acid methyl ester 
• 75-36-5 acetyl chloride 
• 13683-01-7 Diphenylphosphonigsaeure-trimethylsilylester 
• 4559-70-0 Diphenylphosphine oxide 
• 18629-57-7 1-(diphenylphosphanyl)ethan-1-one 
• 108-24-7 acetic anhydride 

Downstream Products

• 21416-24-0 1-Diphenylphosphinoyl-1-diphenylphosphinoyloxyaethan 
• 69737-72-0 3-Diphenylphosphinyl-3-hydroxy-2-butanon-diphenylphosphinat 
• 18629-56-6 1,1-bis(diphenylphosphinoyl)ethanol 

Relevant articles and documents

Chlorosilane-Catalyzed Coupling of Hydrogen Phosphine Oxides with Acyl Chlorides Generating Acylphosphine Oxides

We report a new method for the synthesis of acylphosphine oxides by the direct coupling of hydrogen phosphine oxides and acyl chlorides mediated by chlorosilanes. This new protocol is greener and safer, because it precludes the generation of volatile haloalkanes and the use of oxidants employed in the conventional methods. Moreover, moisture-unstable acylphosphine oxides that are difficult to prepare via the conventional methods can be generated using this new method.