27384-58-3Relevant articles and documents
Enhanced product selectivity in continuous N-methylation of amino alcohols over solid acid-base catalysts with supercritical methanol
Oku, Tomoharu,Ikariya, Takao
, p. 3476 - 3479 (2007/10/03)
The unique properties of supercritical fluids can be exploited for fine-tuning product selectivity. Under the conditions listed for the N-methylation of amino alcohols (see scheme) over solid acid-base bifunctional catalysts, the total yield and product selectivity could be improved. Enhanced product selectivity might be attributed to the milder reaction conditions possible with supercritical methanol, as well as the increased concentration of methanol on the catalyst.
ETUDE DES INTERACTIONS ENTRE FONCTIONS ALCOOL ET AMINE: EVOLUTION THERMIQUE D'HYDROXYDES ET DE SELS D'ω-TRIALKYLAMMONIO ALCANOLS-1
Barbry, Didier,Hasiak, Bruno
, p. 1734 - 1744 (2007/10/02)
The thermolysis of ω-hydroxyalkyltrialkylammonium hydroxides (Φ=4-8) was investigated: Elimination to alkenol competes with substitution to amino alcohol; the hydroxy group can be alkylated into aliphatic ethers by an intermolecular process; the intramolecular cyclization into cyclic ethers is important only when ω=4.Substitution reaction in amino alcohols is the main pathway for the thermolysis of ω-hydroxyalkyltrimethylammonium acetates (ω=5,6) and chloride (ω=6).
