273939-22-3Relevant academic research and scientific papers
MACROCYCLIC SPIROETHERS AS MCL-1 INHIBITORS
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Paragraph 0726; 0727, (2020/07/31)
Provided are compounds represented by Formula (I-A) and the pharmaceutically acceptable salts and solvates thereof, wherein R8, R9a, R9b, R9c, R9d, X, Y, Z, Z1, W, and (aa) are as defined as set forth in the specification. Provided are also compounds of Formula (I-A) for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.
New benzoxazine derivatives useful as integrin receptor antagonists
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, (2008/06/13)
The present invention relates to a class of compounds represented by the formula (I) or a pharmaceutical acceptable salt, prodrug or ester thereof, pharmaceutical compositions comprising compounds of the formula (I), and methods of selectively inhibiting
